| Texto completo | |
| Autor(es): |
Meza, Eveleny Tirsa Vaca
;
Vasquez-Kool, Jorge
;
Sanchez, Noe Ildefonso Costilla
;
Vieira, Amandio
;
Rodrigues, Rodney Alexandre Ferreira
;
Sartoratto, Adilson
;
Granados, Angela del Pilar Flores
;
Tello, Carmen Luisa Marin
;
Ruiz, Ana Lucia Tasca Gois
Número total de Autores: 9
|
| Tipo de documento: | Artigo Científico |
| Fonte: | NATURAL PRODUCT RESEARCH; v. N/A, p. 6-pg., 2023-07-15. |
| Resumo | |
This study evaluated the chemical composition and anti-proliferative activity of essential oils (EOs) obtained by hydrodistillation from seven medicinal plants from Cachicadan, La Libertad Region, Peru. Limonene (0.64 to 44.43%) and linalool (0.36 to 2.12%) were identified in all EOs by gas chromatography coupled to mass spectrometry analysis. The major components (relative intensity & GE; 10%) were cis-dihydro carvone, carvone, and cis-piperitone epoxide for Minthostachys mollis leaves; & beta;-pinene, limonene, and ledol for Lepechinia heteromorpha leaves; limonene, neral, and geranial for Aloysia citriodora, both leaves and flowers; & alpha;-pinene, and limonene for Myrcianthes myrsinoides leaves; and & alpha;-pinene, & beta;-myrcene, and (E)-& beta;-Ocimene for Dalea carthagenensis leaves. Constituted by (Z)-& beta;-ocimene, dihydrotagetone, (Z)-tagetone, and car-3-en-2-one, EO of Tagetes minuta leaves induced an irreversible cytostatic effect against MCF-7 human breast tumor cells. Further in vivo studies must be carried out to establish the safe and efficient dose of T. minuta EO as adjuvant treatment in oncological therapies. (AU) | |
| Processo FAPESP: | 14/23950-7 - Avaliação da atividade (anti)mutagênica in vitro de um alcaloide aporfínico e seus intermediários de síntese |
| Beneficiário: | Tamires Carolina Sedano |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 11/01114-4 - Atividade antiproliferativa e ação hormonal/anti-hormonal de extratos e frações enriquecidas de algumas espécies de Mentha (Lamiaceae) |
| Beneficiário: | Ana Lúcia Tasca Gois Ruiz |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |