| Texto completo | |
| Autor(es): |
Vargas, Jorge Andres Mora
;
Burtoloso, Antonio C. B.
Número total de Autores: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | CHEMSUSCHEM; v. N/A, p. 9-pg., 2023-09-27. |
| Resumo | |
The present study highlights a novel and advantageous protocol for accessing carbamates through the well-established three-component coupling reaction involving CO2, amines, and alkyl halides. By employing an immobilized organic base, operating under mild reaction conditions, an array of alkyl carbamates in yields of up to 95 % could be isolated. This approach offers a broad and versatile product scope, allowing for the facile modification of both the amine and alkyl halide reactants. Notably, the pioneering use of an immobilized organic base, specifically the polymer-supported 1,8-diazabicyclo[5.4.0]undec-7-ene (PS-DBU), in this three-component reaction eliminates the need for classical purification steps, streamlining the process. To ensure practicality and sustainability, extensive studies were conducted to verify the recovery and reusability of the polymer-supported DBU catalyst, which consistently maintained the high chemical yield of the carbamates across multiple cycles. Overall, this innovative protocol represents a significant advancement in carbamate synthesis, combining efficiency, generality, and the potential for DBU recycling. (AU) | |
| Processo FAPESP: | 21/06549-0 - Preparação de isocianatos e polióis de importância industrial a partir de CO2 e plataformas moleculares obtidas a partir da biomassa e seu uso na síntese de poliuretanos |
| Beneficiário: | Jorge Andrés Mora Vargas |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 20/07147-0 - Alfa-heterofuncionalização enantioseletiva de compostos carbonílicos empregando ilídeos sulfoxônios |
| Beneficiário: | Antonio Carlos Bender Burtoloso |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 20/15230-5 - Centro de Pesquisa e Inovação de Gases de Efeito Estufa - RCG2I |
| Beneficiário: | Julio Romano Meneghini |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia |