| Texto completo | |
| Autor(es): |
Chavez, Juliana Helena
;
dos Reis, Vinicius Pinho
;
Silva, Jaqueline Raymondi
;
Laure, Helen Julie
;
Rosa, Jose Cesar
;
Lopes da Fonseca, Benedito Antonio
;
Moraes Figueiredo, Luiz Tadeu
Número total de Autores: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Revista da Sociedade Brasileira de Medicina Tropical; v. 46, n. 1, p. 3-pg., 2013-01-01. |
| Resumo | |
Introduction: West Nile virus (WNV) is a flavivirus with a natural cycle involving mosquitoes and birds. Over the last 11 years, WNV has spread throughout the Americas with the imminent risk of its introduction in Brazil. Methods: Envelope protein domain III of WNV (rDIII) was bacterially expressed and purified. An enzyme-linked immunosorbent assay with WNV rDIII antigen was standardized against mouse immune fluids (MIAFs) of different flavivirus. Results: WNV rDIII reacted strongly with St. Louis encephalitis virus (SLEV) MIAF but not with other flaviviruses. Conclusions: This antigen may be a potentially useful tool for serologic diagnosis and may contribute in future epidemiological surveillance of WNV infections in Brazil. (AU) | |
| Processo FAPESP: | 06/01179-0 - Producao e aplicacao diagnostica de polipeptideos recombinantes derivados da proteina e de flavivirus do complexo da encefalite japonesa. |
| Beneficiário: | Juliana Helena Chávez |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |