Autor(es)

Silva, Luiz E., V ; Moreira, Henrique T. ; Schmidt, Andre ; Romano, Minna M. D. ; Salgado, Helio C. ; Fazan, Rubens, Jr. ; Marin-Neto, J. Antonio ; IEEE

• Tipo de documento: Artigo Científico
• Fonte: 2020 11TH CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS (ESGCO): COMPUTATION AND MODELLING IN PHYSIOLOGY NEW CHALLENGES AND OPPORTUNITIES; v. N/A, p. 2-pg., 2020-01-01.

Resumo

Chagas disease (CD) is caused by the protozoan Trypanosoma cruzi and chronic cardiomyopathy (CC) is its most frequent and ominous consequence. The risk of death of patients with CD has been related to demographic, electrocardiographic-radiological-ultrasonographic and Holter parameters. Cardiac dysautonomia has also been demonstrated and may contribute to the pathogenesis of CC. We hypothesize that heart rate variability (HRV) indices are related to cardiac dysfunction as evaluated with echocardiography, and may configure a noninvasive prognostic marker in patients with CD. Short-term (15 min) cardiac interval series of 23 patients with CD were analyzed using 15 HRV indices and correlated to 7 morpho-functional echocardiographic parameters. Results showed that echocardiographic parameters are correlated with HRV indices, and that distribution entropy seems to be an important index for noninvasive prognostication of CD. (AU)

• Processo FAPESP: 18/21212-0 - Predição da Evolução da Doença de Chagas por meio da Variabilidade da Frequência Cardíaca
• Beneficiário: Luiz Eduardo Virgilio da Silva
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 16/25403-9 - Investigações sobre etiopatogenia, fisiopatologia e terapêutica em humanos e em modelo experimental com a cardiomiopatia da Doença de Chagas
• Beneficiário: José Antonio Marin-Neto
• Modalidade de apoio: Auxílio à Pesquisa - Temático