Virulence factors, antimicrobial resistance and phylogeny of bovine mastitis-associated Streptococcus dysgalactiae

Autor(es)

Crippa, Bruna Lourenco ; Rodrigues, Marjory Xavier ; Tomazi, Tiago ; Yang, Yongqiang ; Rocha, Liliana de Oliveira ; Bicalho, Rodrigo Carvalho ; Silva, Nathalia Cristina Cirone

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF DAIRY RESEARCH; v. 90, n. 2, p. 6-pg., 2023-04-12.

Resumo

We carried out a thorough genetic evaluation of Streptococcus dysgalactiae isolated from clinical bovine mastitis cases and performed a phylogenetic analysis to represent the evolutionary relationship between S. dysgalactiae sequences. A total of 35 S. dysgalactiae strains were isolated from cases of clinical mastitis identified at a large commercial dairy farm located near Ithaca, New York. Whole-genome sequencing identified twenty-six antibiotic resistance genes, four of which were acquired genes, in addition to fifty virulence genes. Multi-locus sequence typing detected three new sequence types (STs). We conclude that a high proportion of this microorganism carries multiple virulence determinants and resistance genes, and that this indicates its potential to cause mastitis. Eight different STs were identified, of which ST453 (n = 17) was the most prevalent and ST714, ST715, ST716 were novel STs. (AU)

• Processo FAPESP: 18/24191-3 - Investigação genômica de Staphylococcus coagulase negativa isolados de vacas com mastite
• Beneficiário: Nathalia Cristina Cirone Silva
• Modalidade de apoio: Bolsas no Exterior - Pesquisa