| Texto completo | |
| Autor(es): |
Di Filippo, Leonardo Delello
;
de Paula, Mariana Carlomagno
;
Duarte, Jonatas Lobato
;
de Paula, Geanne Aparecida
;
Frigieri, Isadora
;
Chorilli, Marlus
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Expert Opinion on Drug Delivery; v. 20, n. 6, p. 19-pg., 2023-06-14. |
| Resumo | |
IntroductionSkin cancer is the most common form of cancer worldwide, with increasing incidence rates in recent years. Although conventional chemotherapy and radiation therapy have been used for its treatment, these therapies have several limitations such as lack of selectivity and significant side effects. Targeted nanocarriers have emerged as a promising approach for the treatment of skin cancer.Areas coveredThis review article provides an overview of targeted nanocarriers for skin cancer treatment. It covers the various types of targeted nanocarriers, including liposomes, polymeric nanoparticles, dendrimers, and inorganic nanoparticles.Expert opinionThere are still several challenges that need to be addressed before the clinical translation of targeted nanoparticles, such as optimization of their properties, development of reliable and robust characterization methods, and evaluation of their safety and efficacy in clinical trials. Another key aspect for the advancement of these studies is the need to improve regulatory aspects related to the toxicity and regulation of nanomedicines targeting skin cancer. Overall, targeted nanocarriers hold great potential for the development of safe and effective treatments for skin cancer, which can contribute to a better prognosis and overall patients' life quality. (AU) | |
| Processo FAPESP: | 19/25125-7 - Nanoemulsões contendo terpenos como potenciais larvicidas e repelentes contra Aedes aegypti (Linnaeus, 1762) |
| Beneficiário: | Jonatas Lobato Duarte |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 19/17913-5 - Desenvolvimento farmacotécnico e atividade anti-Candida albicans in vitro e in vivo de carreadores lipídicos nanoestruturados dispersos em hidrogéis para administração vaginal de hipericina |
| Beneficiário: | Marlus Chorilli |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 20/12622-0 - Avaliação do potencial de carreadores lipídicos nanoestruturados funcionalizados com cetuximabe dispersos em hidrogéis termo-responsivos mucoadesivos para administração intranasal de temozolomida no tratamento do Glioblastoma Multiforme |
| Beneficiário: | Leonardo Delello Di Filippo |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |