Simple Electroanalytical Method for Determination of Guanosine in Biological Sample

Autor(es)

dos Santos, Daniela Pereira ; Totta Brunelli, Tamara Fernanda ; Bianchi, Alex Rodrigo ; Boldrin Zanoni, MariaValnice

• Tipo de documento: Artigo Científico
• Fonte: ANALYTICAL & BIOANALYTICAL ELECTROCHEMISTRY; v. 2, n. 4, p. 10-pg., 2010-12-01.

Resumo

A poly glutamic acid film modified electrode exhibited a catalytic response to guanosine oxidation potential and higher peak current value. Linear concentration curve was obtained in the concentration interval of 1.0 a 10.0 mu mol L-1 in 0.04 mol L-1 B-R buffer pH 2.0 with a detection limit of 0.198 mu mol L-1. The electrode was used for the determination of guanosine in the potential of + 1.1 V (vs. Ag/AgCl) using differential pulse voltammetry (DPV) at urine sample with good recovery. (AU)

• Processo FAPESP: 03/06598-3 - Desenvolvimento de eletrodos modificados com poli acido glutamico e sua aplicacao na analise de compostos antioxidantes e farmaceuticos.
• Beneficiário: Daniela Pereira dos Santos
• Modalidade de apoio: Bolsas no Brasil - Doutorado