Eradication of Salmonella Typhimurium in broiler chicks by combined use of P22 bacteriophage and probiotic

Autor(es)

Marietto-Goncalves, Guilherme Augusto ; Lima, Edna Tereza ; Donato, Tais Cremasco ; Rocha, Ticiane Sousa ; Cisneros Alvarez, Luis Emiliano ; Sequeira, Julio Lopes ; Andreatti Filho, Raphael Lucio

• Tipo de documento: Artigo Científico
• Fonte: MICROBIOLOGY RESEARCH; v. 2, n. 1, p. 6-pg., 2011-01-01.

Resumo

It has been reported that the phage therapy is effective in controlling the number of colony-forming unit (CFU) of Salmonella spp. in chicken gut. This paper describes the protective effect of phage and Lactobacilli administration on Salmonella infection in 1-day-old chicks. We administered the bacteriophage P22 in a single dose and a probiotic mixture of four species of bacteriocin-producing Lactobacillus once a day for one week. Samples were analyzed every 48 hours, and intestinal eradication of S. Typhimurium was confirmed after treatments. We observed an increase in the size of duodenal villi and cecal crypts, as well as an increase in body weight in groups that received daily doses of Lactobacilli. This study confirms the efficiency of bacteriophage therapy in controlling salmonellosis in chicks and the beneficial effect of Lactobacilli mixtures in the weight gain of the birds. (AU)

• Processo FAPESP: 07/54012-9 - Utilização de bacteriófagos e Lactobacillus spp. no tratamento de frango de corte (Gallus gallus domesticus - Linnaeus, 1758) experimentalmente inoculados com Salmonella enterica subs. enterica sorotipo typhimurium
• Beneficiário: Guilherme Augusto Marietto Gonçalves
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 08/51034-4 - Utilização do bacteriófago P22 em associação com amostras de Lactobacillus spp. no tratamento de frangos de corte inoculados experimentalmente com Salmonella enterica subs. enterica sorotipo Typhimurium
• Beneficiário: Raphael Lucio Andreatti Filho
• Modalidade de apoio: Auxílio à Pesquisa - Regular