Children Living near a Sanitary Landfill Have Increased Breath Methane and Methanobrevibacter smithii in Their Intestinal Microbiota

Autor(es)

de Araujo Filho, Humberto Bezerra ; Carmo-Rodrigues, Mirian Silva ; Mello, Carolina Santos ; Fonseca Lahoz Melli, Ligia Cristina ; Tahan, Soraia ; Campos Pignatari, Antonio Carlos ; de Morais, Mauro Batista

• Tipo de documento: Artigo Científico
• Fonte: ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL; v. 2014, p. 6-pg., 2014-01-01.

Resumo

This study evaluated the breath CH 4 excretion and concentration of M. smithii in intestinal microbiota of schoolchildren from 2 slums. One hundred and eleven children from a slum near a sanitary landfill, 35 children of a slum located away from the sanitary landfill, and 32 children from a high socioeconomic level school were included in the study. Real-time PCR was performed to quantify the M. smithii nifH gene and it was present in the microbiota of all the participating children, with higher (P < 0.05) concentrations in those who lived in the slum near the landfill (3.16 x 10(7) CFU/g of feces), comparing with the children from the slum away from the landfill (2.05 x 10(6) CFU/g of feces) and those from the high socioeconomic level group (3.93 x 10(5) CFU/g of feces). The prevalence of children who present breath methane was 53% in the slum near the landfill, 31% in the slum further away from the landfill and, 22% in the high socioeconomic level group. To live near a landfill is associated with higher concentrations of M. smithii in intestinal microbiota, comparing with those who live away from the landfill, regardless of their socioeconomics conditions. (AU)

• Processo FAPESP: 09/18458-8 - Interação da microbiota intestinal e da função digestivo-absortiva com o ambiente social e a condição nutricional: distúrbios intestinais como argumentos para reduzir iniquidades
• Beneficiário: Mauro Batista de Morais
• Modalidade de apoio: Auxílio à Pesquisa - Regular