Spray drying of lipid nanosystems (SLN and NLC) loaded with Syzygium aromaticum essential oil

Autor(es)

Rosa, D. M. ; Oliveira, W. P. ; Carcel, JA ; Clemente, G ; GarciaPerez, JV ; Mulet, A ; Rossello, C

• Tipo de documento: Artigo Científico
• Fonte: IDS'2018: 21ST INTERNATIONAL DRYING SYMPOSIUM; v. N/A, p. 8-pg., 2018-01-01.

Resumo

A quality by design approach was used to investigate the influence of formulation composition and spray drying conditions on physicochemical properties of redispersable lipid based nanosystems loaded with Syzygium aromaticum essential oil. Four critical independent variables were studied: presence or absence of the liquid lipid oleic acid (0% - 1%), of the cationic surfactant CTAB (0% and 1%), inlet drying temperature (60 degrees C -80 degrees C), and ratio of the drying aids (ADJ) regarded to total formulation constituents weight (1:1 and 2:1). Resuls showed the production of spray dried redispersable lipid systems loaded with essential is feasible under very restrict conditions. (AU)

• Processo FAPESP: 11/10333-1 - Microencapsulação e nanoencapsulação de ativos naturais empregando tecnologias de secagem
• Beneficiário: Cláudia Regina Fernandes de Souza
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 14/15905-1 - Encapsulação de óleos essenciais em carreadores lipídicos: desenvolvimento tecnológico e aplicações
• Beneficiário: Wanderley Pereira Oliveira
• Modalidade de apoio: Auxílio à Pesquisa - Regular