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Heart-rate modulation of non-vascularized epidermis optical attenuation coefficient

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Autor(es):
Martinelli, Matheus B. ; Dominguez, Christian T. ; Bachmann, Luciano ; Cardoso, George C. ; Tuchin, VV ; Leahy, MJ ; Wang, RK
Número total de Autores: 7
Tipo de documento: Artigo Científico
Fonte: DYNAMICS AND FLUCTUATIONS IN BIOMEDICAL PHOTONICS XVI; v. 10877, p. 7-pg., 2019-01-01.
Resumo

Video plethysmography (vPPG) is a noninvasive, remote diagnostics method that monitors cardiac activity by measuring subtle variations in the optical properties of skin driven by heart pulsations. However, the origin of the fluctuations in skin color at the heart rate responsible for the vPPG signal is not well understood. Using optical coherence tomography (OCT), we show evidence that the optical attenuation coefficient of the outermost layer of the epidermis is modulated at heart rate, being the modulation surrogate for the mechanical changes in the skin. We propose a hydraulic shock hypothesis to explain the phenomenon. The mechanical modulation of the non-vascularized epidermis would explain the modulation of optical properties of superficial skin, allowing for detection of pulsation even for non-penetrating radiation wavelengths such as blue light, as it is often observed. (AU)

Processo FAPESP: 17/01932-5 - Determinação da frequência cardíaca e mapeamento do tempo de trânsito do pulso sanguíneo utilizando técnicas de vídeo
Beneficiário:Matheus Bigatão Martinelli
Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
Processo FAPESP: 13/07276-1 - CEPOF - Centro de Pesquisa em Óptica e Fotônica
Beneficiário:Vanderlei Salvador Bagnato
Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs