Association Between the Predictors of Functional Capacity and Heart Rate Off-Kinetics in Patients with Chronic Obstructive Pulmonary Disease

Autor(es)

Camargo, Patricia Faria ; Ditomaso-Luporini, Luciana ; Soares de Carvalho Jr, Luiz Carlos ; Goulart, Cassia da Luz ; Sebold, Rayane ; dos Santos, Polliana Batista ; Roscani, Meliza Goi ; Borghi-Silva, Audrey

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE; v. 15, p. 10-pg., 2020-01-01.

Resumo

Background: The heart rate (HR) kinetics as well as other predictors of functional capacity such as the Chronic Obstructive Pulmonary Disease (COPD) Assessment Test (CAT), the Duke Activity Status Index (DASI) and the handgrip strength (HGS) represent important tools in assessing the impact of COPD on exercise performance and health status of individuals with COPD. Purpose: To verify the relationship between functional capacity, measured using the six-minute walking test (6MWT), with the HR off-kinetics, HGS and the DASI and CAT scores. Methods: For this cross-sectional study, 29 subjects with COPD underwent body composition, pulmonary function and cardiac function tests. Subsequently, the DASI and CAT questionnaires and HGS test were performed. The beat-to-beat R-R intervals (IRR) were collected in rest, during the test and in recovery after the 6MWT. The HR off-kinetics was obtained during a 360-second period in post-exercise recovery through the HR mono-exponential decay. Results: Moderate correlations were observed between: 1) walked distance (WD) in the 6MWT and the CAT and DASI scores (r= -0.58, p=0.001 and r= 0.58, p=0.001, respectively); 2) WD and HGS (r=0.37, p=0.05); 3) and WD and HR off-kinetics (t; r= -0.54, p=0.002 and MRT; r= -0.55, p=0.002, respectively). Conclusion: The 6MWT performance is a direct measurement to evaluate functional capacity. Additionally, it is related to other direct and indirect markers for functional evaluation in patients with COPD. These results suggest the application of these tools in clinical practice, based on the accessibility, non-invasive character and easy applicability of these methods. (AU)

• Processo FAPESP: 18/00860-3 - Avaliação da modulação autonômica cardíaca e da capacidade funcional na sobreposição da Doença Pulmonar Obstrutiva Crônica Síndrome da Apnéia Obstrutiva do Sono
• Beneficiário: Patrícia Faria Camargo
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 15/26501-1 - Estudo dos fatores limitantes ao exercício físico e efeitos dos recursos adjuntos à reabilitação nas doenças cardiorrespiratórias crônicas: uma abordagem multicêntrica
• Beneficiário: Audrey Borghi Silva
• Modalidade de apoio: Auxílio à Pesquisa - Temático