| Texto completo | |
| Autor(es): |
Colnago, Luiz Alberto
;
Trevisol, Iara Maria
;
Voss Rech, Daiane
;
Forato, Lucimara Aparecida
;
Igreja do Nascimento Mitre, Cirlei
;
Gagliardi Leite, Jose Paulo
;
Giglioti, Rodrigo
;
Okino, Cintia Hiromi
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH; v. 17, n. 18, p. 9-pg., 2020-09-01. |
| Resumo | |
The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and efficient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus efficacy of the proposed films. Polystyrene petri dishes were covered with a thin layer of detergent formula. After drying, the films were exposed to different virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 10(3.7)to 10(6.7)EID(50)), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19. (AU) | |
| Processo FAPESP: | 19/13656-8 - Desenvolvimento e aplicações da ressonância magnética nuclear em produtos e processos de interesse agropecuário |
| Beneficiário: | Luiz Alberto Colnago |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |