| Texto completo | |
| Autor(es): |
de Oliveira, Jose Diogo
;
Macedo, Carlos Fernando
;
de Oliveira Guarnieri, Joao Paulo
;
Theizen, Thais Holtz
;
Machado, Daisy
;
Lancellotti, Marcelo
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | GENETICS AND MOLECULAR BIOLOGY; v. 44, n. 1, p. 5-pg., 2020-01-01. |
| Resumo | |
S. pneumoniae, commonly known as pneumococcus, is a naturally competent Gram-positive bacterium and is the major cause of pneumonia in elderly and children in developing countries. This pathogen is associated with respiratory diseases affected by pollution. The objective of this work was determining the effect of ash and environmental dust from the burning of sugarcane on pneumococci bacterial transformation. The transformation capacity of the Pn360 pneumococci strain was performed using the assays of DNA donor of mutant for luxS gene. Thus, the transformation tests were performed in contact with dust collected in the southwestern region of Brazil (important region where burning of sugar cane is present in the agriculture). The use of degradative practices in the sugar cane agriculture in Brazil was involved in the transformation capacity of the S. pneumoniae. This phenomenon includes important consequences for public health concerning to resistance acquisition and new virulence factors of this important infection. In conclusion, we obtained important results concerning the action of environmental pollution in Streptococcus pneumoniae transformation, increasing the DNA acquisition for this pathogen. (AU) | |
| Processo FAPESP: | 11/14079-2 - Uso de nanopartículas em vacinas contra meningites bacterianas |
| Beneficiário: | Marcelo Lancellotti |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 12/15046-3 - Estudo do genoma e metaboloma de linhagens de Haemophilus influenzae biótipo aegyptius causadores da febre púrpura brasileira |
| Beneficiário: | Marcelo Lancellotti |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 18/09874-7 - Análise e utilização do genoma de Haemophilus influenzae biotipo aegyptius para fins biotecnológicos |
| Beneficiário: | Marcelo Lancellotti |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |