| Texto completo | |
| Autor(es): |
Lima, Cecilia Beatriz Nascimento
;
Joly, Mariana Montini
;
Moraes, Luiz Alberto Beraldo
;
Consoli, Fernando Luis
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | INSECTS; v. 15, n. 9, p. 22-pg., 2024-09-01. |
| Resumo | |
The within-species diversity of Streptomyces nojiriensis and Streptomyces novaecaesareae in producing bioactive compounds against Spodoptera frugiperda larvae is demonstrated, leading to the identification of valinomycin and naphtomycin from S. novaecaesareae as the bioactive molecules. The potential use of these molecules as alternative strategies for the sustainable management of Spodoptera frugiperda larvae is discussed. The Streptomyces genus has long been recognized as a prolific and valuable source of diverse secondary metabolites. These metabolites contribute significantly to the intricate chemical diversity exhibited by Streptomyces, making them an indispensable reservoir for drug discovery, agricultural applications, and industrial processes. Exploiting the potential of these natural compounds holds the promise of ushering in a new era in insect pest management, reducing reliance on synthetic chemicals and fostering ecologically sustainable solutions. This study dives into the realm of chemo diversity within isolates of Streptomyces nojiriensis and Streptomyces novaecaesareae, with a specific focus on the production of insecticidal compounds. We explored chromatographic techniques for the identification and isolation of insecticidal compounds, and two bioactive compounds were identified in extracts of S. novaecaesareae. Valinomycin was identified from hexanic extracts of strain Asp59, while naphthomycin from ethyl acetate extracts of strain Asp58. These compounds showed insecticidal activity against first instars of Spodoptera frugiperda (Asp59: LC50 = 10.82 mu g/mu L, LC90 = 26.25 mu g/mu L; Asp58: LC50 = 15.05 mu g/mu L, LC90 = 38.84 mu g/mu L). Notably, this is the first report of naphthomycin as an insecticidal compound. The present study suggests that valinomycin and naphthomycin may be a novel biological source for the control of Spodoptera frugiperda in early stages. (AU) | |
| Processo FAPESP: | 20/01018-4 - As duas faces do microbioma de insetos no desenvolvimento de alternativas sustentáveis para o manejo de Spodoptera frugiperda e Euschistus heros |
| Beneficiário: | Cecília Beatriz Nascimento Lima |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 22/11113-0 - Explorando espécies de Pseudomonas associadas a insetos como fonte de novos compostos inseticidas para o manejo sustentável de insetos pragas |
| Beneficiário: | Mariana Montini Joly |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 11/50877-0 - Diversidade, ecologia e potencial biotecnológico da bacteriofauna simbionte associada a insetos |
| Beneficiário: | Fernando Luis Cônsoli |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa BIOTA - Temático |