Structure and absolute configuration of a secolignan from Peperomia blanda

Autor(es)

Felippe, Lidiane G. ^[1] ; Batista, Jr., Joao M. ^[1] ; Baldoqui, Debora C. ^[2] ; Nascimento, Isabele R. ^[1] ; Kato, Massuo J. ^[3] ; Bolzani, Vanderlan S. ^[1] ; Furlan, Maysa ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista UNESP, Inst Quim, BR-14800900 Araraquara, SP - Brazil

^[2] Univ Estadual Maringa, Dept Quim, BR-87020900 Maringa, PR - Brazil

^[3] Univ Sao Paulo, Inst Quim, BR-05599970 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: PHYTOCHEMISTRY LETTERS; v. 4, n. 3, p. 245-249, SEP 2011.
• Citações Web of Science: 13

Resumo

A secolignan, (-)-2-methyl-3-{[}bis(3 `,4 `-methylenedioxy-5 `-methoxyphenyl) methyl] butyrolactone (1), with a rare cis configuration was isolated from the aerial parts of Peperomia blanda (Piperaceae). The structure of this compound was elucidated by a combination of spectroscopic methods, including ultraviolet, infrared, 1D- and 2D- nuclear magnetic resonance as well as high resolution mass spectrometry data. The absolute configuration of (-)-1 was determined as (2R,3S) by the comparison of experimental electronic circular dichroism (ECD) spectroscopy and time-dependent density functional theory (TDDFT) calculations. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 03/11524-9 - Biossíntese em espécies de Celastraceae, Hippocrateaceae e Piperaceae: análise do metaboloma - proteoma de metabólitos secundários com potencial biológico
• Beneficiário: Maysa Furlan
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 05/57042-0 - Origem biossintética e aspectos evolutivos de metabólitos secundários de angiopermas basais
• Beneficiário: Massuo Jorge Kato
• Modalidade de apoio: Auxílio à Pesquisa - Regular