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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Maternal smoking during pregnancy: Impact on otoacoustic emissions in neonates

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Autor(es):
Durante, Alessandra Spada [1] ; Ibidi, Silvia Maria [2] ; Becker Lotufo, Joao Paulo [3] ; Carvallo, Renata M. M. [4]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Santa Casa Sch Med Sci Sao Paulo FCMSCSP, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Med, Dept Neonatol, Sao Paulo - Brazil
[3] Univ Sao Paulo, Univ Hosp, Antismoking Program, Sao Paulo - Brazil
[4] Univ Sao Paulo, Sch Med FMUSP, Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: International Journal of Pediatric Otorhinolaryngology; v. 75, n. 9, p. 1093-1098, SEP 2011.
Citações Web of Science: 14
Resumo

Objectives: To determine the effect of maternal smoking during pregnancy on transient evoked otoacoustic emissions levels in neonates. Methods: This was a cross-sectional study investigating neonates in the maternity ward of a university hospital in the city of Sao Paulo, Brazil. A total of 418 term neonates without prenatal or perinatal complications were evaluated. The neonates were divided into two groups: a study group, which comprised 98 neonates born to mothers who had smoked during pregnancy; and a control group, which comprised 320 neonates born to mothers who had not. In order to compare the two ears and the two groups in terms of the mean overall response and the mean transient evoked otoacoustic emissions in response to acoustic stimuli delivered at different frequencies, we used analysis of variance with repeated measures. Results: The mean overall response and the mean frequency-specific response levels were lower in the neonates in the study group (p < 0.001). The mean difference between the groups was 2.47 dB sound pressure level (95% confidence interval: 1.47-3.48). Conclusions: Maternal smoking during pregnancy had a negative effect on cochlear function, as determined by otoacoustic emissions testing. Therefore, pregnant women should be warned of this additional hazard of smoking. It is important that smoking control be viewed as a public health priority and that strategies for treating tobacco dependence be devised. (C) 2011 Elsevier Ireland Ltd. All rights reserved. (AU)

Processo FAPESP: 01/09605-5 - Efeito da atenuação das emissões otoascústicas em prematuros nos primeiros meses de vida
Beneficiário:Renata Mota Mamede Carvallo
Modalidade de apoio: Auxílio à Pesquisa - Regular