Five Weeks of Sprint Interval Training Improve Muscle Glycolytic Content and Activity But Not Time to Task Failure in Severe-Intensity Exercise

Autor(es)

De Poli, Rodrigo Araujo Bonetti ; Murias, Juan Manuel ; Antunes, Barbara Moura ; Marinari, Gabriele ; Dutra, Yago Medeiros ; Milioni, Fabio ; Zagatto, Alessandro Moura

• Tipo de documento: Artigo Científico
• Fonte: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE; v. 56, n. 8, p. 13-pg., 2024-08-01.

Resumo

PurposeThis study examined the impact of a 5-wk sprint interval training (SIT) intervention on time to task failure (TTF) during severe-intensity constant work rate (CWR) exercise, as well as in glycolytic enzymatic content and activity, and glycogen content.MethodsFourteen active males were randomized into either a SIT group (n = 8) composed of 15 SIT sessions over 5 wk, or a control group (n = 6). At pretraining period, participants performed i) ramp incremental test to measure the cardiorespiratory function; ii) CWR cycling TTF at 150% of the power output (PO) at the respiratory compensation point (RCP-PO) with muscle biopsies at rest and immediately following task failure. After 5 wk, the same evaluations were repeated (i.e., exercise intensities matched to current training status), and an additional cycling CWR matched to pretraining 150% RCP-PO was performed only for TTF evaluation. The content and enzymatic activity of glycogen phosphorylase (GPhos), hexokinase (HK), phosphofructokinase (PFK), and lactate dehydrogenase (LDH), as well as the glycogen content, were analyzed. Content of monocarboxylate transporter isoform 4 (MCT4) and muscle buffering capacity were also measured.ResultsDespite improvements in total work performed at CWR posttraining, no differences were observed for TTF. The GPhos, HK, PFK, and LDH content and activity, and glycogen content also improved after training only in the SIT group. Furthermore, the MCT4 concentrations and muscle buffering capacity were also improved only for the SIT group. However, no difference in glycogen depletion was observed between groups and time.ConclusionsFive weeks of SIT improved the glycolytic pathway parameters and total work performed; however, glycogen depletion was not altered during CWR severe-intensity exercise, and TTF remained similar. (AU)

• Processo FAPESP: 18/21126-6 - Fadiga no exercício supramáximo: Análise da influência de mecanismos central e periférico, acidose muscular, substrato energético, atividade enzimática e metabólitos
• Beneficiário: Alessandro Moura Zagatto
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 19/17445-1 - Influência do treinamento intervalado de alta intensidade no tempo até a exaustão em esforço supramáximo: respostas biomoleculares e neuromusculares
• Beneficiário: Rodrigo de Araujo Bonetti de Poli
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 21/08479-0 - Time course da recuperação neuromuscular após sessão de treino de corrida: influência da intensidade, da imersão em água quente e da imersão em água fria
• Beneficiário: Yago Medeiros Dutra
• Modalidade de apoio: Bolsas no Brasil - Doutorado