HIV-Infected Individuals Do Not Present Significant Differences regarding Periodontal Status: A Systematic Review and Meta-Analysis

Autor(es)

Teixeira, Lucas Ribeiro ; Pena, Diana Estefania Ramos ; Castro, Leticia Rodrigues de ; dos Santos, Marcia ; Saraiva, Maria da Conceicao Pereira ; Chahud, Fernando ; Pozzetto, Bruno ; Lourenco, Alan Grupioni ; Motta, Ana Carolina Fragoso

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF DENTISTRY; v. 2024, p. 17-pg., 2024-08-26.

Resumo

Objective. To evaluate, through a systematic literature review, whether periodontal status in HIV-infected individuals is different from those non-HIV-infected. Materials and Methods. A systematic search for published observational studies within six electronic databases and grey literature was conducted, PROSPERO database number CRD42020160062. Results from studies reporting clinical periodontal parameters: probing pocket depth, bleeding on probing, clinical attachment level, plaque index, and gingival index, in HIV- and non-HIV-infected individuals were reviewed. The quality of the assessment was evaluated according to the Joanna Briggs Institute Appraise Checklist. Results. Twenty-three observational studies met the eligibility criteria and were included for analysis. The qualitative analysis indicated similarities in periodontal parameters within both groups, with no significant mean difference (MD) within both groups regarding clinical periodontal parameters; severe heterogeneity was also detected. Conclusions. No significant differences were found in the periodontal profile of HIV-infected and non-HIV-infected individuals. However, the high heterogeneity among the studies calls for caution in interpreting these findings. Further investigations using standardized methods for periodontal evaluation are needed to clarify the association between HIV infection and periodontal conditions. (AU)

• Processo FAPESP: 16/22476-5 - Influência do tratamento periodontal sobre os níveis de marcadores inflamatórios orais em pacientes infectados pelo HIV
• Beneficiário: Vanessa de Oliveira Teles
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 18/23031-2 - Relação entre a infecção pelo vírus da imunodeficiência humana (HIV-1) e a periodontite.
• Beneficiário: Ana Carolina Fragoso Motta
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 22/08308-3 - Novas tendências na pesquisa da infecção pelo HIV-1 e Periodontite: translocação microbiana, inflamação sistêmica e reservatórios virais
• Beneficiário: Ana Carolina Fragoso Motta
• Modalidade de apoio: Auxílio à Pesquisa - Regular