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Organocatalytic Enantioselective Syntheses of Flavonoids and Cannabinoids

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Autor(es):
Vidal-Albalat, Andreu ; Matos Paz, Bruno
Número total de Autores: 2
Tipo de documento: Artigo Científico
Fonte: ADVANCED SYNTHESIS & CATALYSIS; v. 366, n. 5, p. 12-pg., 2023-11-28.
Resumo

Flavonoids and cannabinoids comprise two large families of natural products that contain a chromane moiety in their structure. Their therapeutic potential has been extensively investigated as potential treatments to several diseases, ranging from cancer to infectious and neurodegenerative diseases. Despite their relative structural simplicity, in recent years creative synthetic methodologies were designed to overcome limitations from the previous synthetic strategies applied to these compounds. The aim of this review is to provide a comprehensive overview of all the enantioselective organocatalytic strategies that have been applied to the synthesis of flavonoids and cannabinoids to date. image (AU)

Processo FAPESP: 22/14310-0 - Relações lineares de energia livre em catálise assimétrica
Beneficiário:Bruno Matos Paz
Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores