Estimation of standing height in spina bifida: model development and validation

Autor(es)

Bertapelli, Fabio ; Leonardi-Figueiredo, Marisa Maia ; Martins, Emanuela Juvenal ; de Baptista, Cyntia Rogean de Jesus Alves ; Mattiello-Sverzut, Ana Claudia

• Tipo de documento: Artigo Científico
• Fonte: Jornal de Pediatria; v. 100, n. 6, p. 7-pg., 2024-10-01.

Resumo

Objective: Childhood standing height has been estimated from arm span-related (height(AS)) models. The authors aimed to develop and cross-validate a height(AS) model in individuals with spina bifida (SB) and examine the accuracy of existing height(AS) models. Methods: Participants were individuals with sacral and low-lumbar SB (n = 14) and non-SB (n = 83), 7-16 years old. Arm span, age, sex, and group (SB vs. non-SB) were candidate height predictors. Sequential regression and leave-one-out cross-validation approaches were used for the model development (M1) and cross-validation (M1-M5). Existing models were: an SB-specific model from Polfuss et al. (M2) and non-SB specific models from Gauld et al. (M3), Mulu et al. (M4), and Zverev et al. (M5) studies. Results: Arm span and group explained 95 % of the variance in height (R-2 = 0.95; p < 0.001; SEE = 3.666 cm) and were included in the M1. Mean differences between actual and estimated height were 0.0 cm (M1), 0.4 cm (M2), and 0.5 cm (M5), all not significant (p > 0.05). However, Bland-Altman analysis revealed some variability in the predictability of the models across participants with limits of agreement ranging from 7.4 to 10.9 cm. Considerable errors were observed with M3 (mean diff: -5.58 cm, 95 % CI: -1.6, -20.2 cm), and M4 (mean diff: 10.5 cm, 95 % CI: -13.8, -27.3 cm). Conclusions: Models (M1, M2 and M5) may accurately estimate standing height in groups of children with SB. However, due to the wide limits of agreement, caution is recommended when applying these models for individual height estimations. (c) 2024 Published by Elsevier Editora Ltda. on behalf of Sociedade Brasileira de Pediatria. (AU)

• Processo FAPESP: 22/00099-6 - Percepção de Esforço (OMNI) para crianças e adolescentes com doenças neurológicas crônicas - validação da versão adaptada da escala às crianças e adolescentes usuárias de cadeiras de rodas
• Beneficiário: Fábio Bertapelli
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 17/17596-4 - Capacidade aeróbia, força e potência muscular de crianças e adolescentes com doenças crônicas: caracterização e tratamento
• Beneficiário: Ana Cláudia Mattiello-Sverzut
• Modalidade de apoio: Auxílio à Pesquisa - Temático