Vaccination Coverage at Birth in Brazil: Spatial and Temporal Trends in the Impact of COVID-19 on Uptake of BCG and Hepatitis B Vaccines

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Alves, Yan Mathias ; Berra, Thais Zamboni ; Tavares, Reginaldo Bazon Vaz ; Zini, Nathalia ; Ferreira, Quezia Rosa ; Andrade, Licia Kellen de Almeida ; Tartaro, Ariela Fehr ; Pelodan, Maria Eduarda Pagano ; Vigato, Beatriz Fornaziero ; Silveira, Beatriz Kuroda ; Assumpcao, Ana Luiza Brasileiro Nato Marques ; Popolin, Marcela Antunes Paschoal ; Curvo, Patricia Abrahao ; Protti-Zanatta, Simone ; Serrano-Gallardo, Maria Del Pilar ; Arcencio, Ricardo Alexandre ; Palha, Pedro Fredemir ; Ballestero, Jaqueline Garcia de Almeida

• Tipo de documento: Artigo Científico
• Fonte: VACCINES; v. 12, n. 12, p. 13-pg., 2024-12-01.

Resumo

Introduction: Vaccines are a significant public health achievement, which are crucial for child survival and disease control globally. In Brazil, the National Immunization Program (PNI) manages vaccination schedules, including essential vaccines like BCG and Hepatitis B, administered at birth. Despite achieving over 95% coverage for years, vaccination rates have declined since 2016, a trend exacerbated by the COVID-19 pandemic. This study aims to analyze spatial and temporal trends in BCG and Hepatitis B vaccination coverage at birth, identify areas with spatial variation in these trends, classify the identified trends, and investigate the pandemic's impact on vaccination adherence. Methods: This is an ecological study with real-world data from Brazil, focusing on vaccination coverage from 2014 to 2023. Utilizing the Spatial Variation in Temporal Trends (SVTT) technique, the study identifies municipalities' vaccination trends. It also employs time series analysis and Interrupted Time Series methods to evaluate the pandemic's impact on vaccination rates, using data from the PNI and the Information System on Live Births (SINASC). Results: Between January 2014 and December 2023, Brazil administered 25,902,207 doses of the BCG vaccine to children at birth, with 3911 municipalities (70.24%) showing declining trends, particularly in Florian & oacute;polis. Similarly, 22,962,434 doses of the Hepatitis B vaccine were administered, with 3284 municipalities also experiencing declines. Conclusions: It is crucial that public health policies be reevaluated to address regional disparities in vaccination coverage, particularly in more vulnerable areas. Focused interventions, such as awareness campaigns, improved access to vaccination services, and strengthened monitoring, are fundamental to reversing this trend. (AU)

• Processo FAPESP: 22/08510-7 - Interação e efeito da pandemia por COVID-19 no controle da Tuberculose no Estado de São Paulo: aspectos político-sociais, clínico-epidemiológicos e práticas inovadoras
• Beneficiário: Ricardo Alexandre Arcêncio
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 23/01758-6 - Impacto da COVID-19 no controle da Tuberculose no Estado de São Paulo-Brasil: análise dos indicadores de morbimortalidade e estratégias de enfrentamento pela saúde digital
• Beneficiário: Yan Mathias Alves
• Modalidade de apoio: Bolsas no Brasil - Doutorado