| Texto completo | |
| Autor(es): Mostrar menos - |
Carmona, Rita Cassia Compagnoli
;
Reis, Fabricio Caldeira
;
Cilli, Audrey
;
Dias, Juliana Monti Maifrino
;
Machado, Braulio Caetano
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de Morais, Daniele Rita
;
Jorge, Adriana Vieira
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Dias, Amanda Meireles Nunes
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de Sousa, Cleusa Aparecida
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Calou, Sabrina Bonetti
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Ferreira, Gabriel Henriques
;
Leme, Lucas
;
Timenetsky, Maria do Carmo Sampaio Tavares
;
Eduardo, Maria Bernadete de Paula
Número total de Autores: 14
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| Tipo de documento: | Artigo Científico |
| Fonte: | Viruses-Basel; v. 16, n. 12, p. 20-pg., 2024-12-01. |
| Resumo | |
In the context of the near-global eradication of wild poliovirus, the significance of non-polio enteroviruses (NPEVs) in causing acute flaccid paralysis (AFP) and their impact on public health has gained increased attention. This research, conducted from 2001 to 2021, examined stool samples from 1597 children under 15 years in S & atilde;o Paulo, Brazil, through the AFP/Poliomyelitis Surveillance Program, detecting NPEVs in 6.9% of cases. Among the 100 NPEV-positive strains analyzed, 90 were genotyped through genomic sequencing of the partial VP1 region, revealing a predominance of EV-B species (58.9%), followed by EV-A (27.8%) and EV-C (13.3%). This study identified 31 unique NPEV types, including EV-A71, CVB2, and E11, as the most prevalent, along with the first documented occurrence of CVA19 in Brazil. These findings emphasize the importance of NPEV genotyping in distinguishing AFP from poliomyelitis, enhancing understanding of these viruses' epidemiology. Moreover, it ensures that AFP cases are correctly classified, contributing to the effective surveillance and eradication efforts for poliomyelitis. (AU) | |
| Processo FAPESP: | 17/05350-0 - Diversidade genética dos Enterovirus não-pólio detectados em pacientes com quadro de paralisia flácida aguda no estado de São Paulo |
| Beneficiário: | Rita de Cássia Compagnoli Carmona |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 17/50333-7 - Plano de desenvolvimento institucional em pesquisa do Instituto Adolfo Lutz (PDIp) |
| Beneficiário: | Carlos Henrique Camargo |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa Modernização de Institutos Estaduais de Pesquisa |
| Processo FAPESP: | 18/21193-5 - EMU concedido no processo 2017/50333-7: sequenciador genético de DNA |
| Beneficiário: | Carlos Henrique Camargo |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa Equipamentos Multiusuários |