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A simple and low-cost disposable biosensor to determine microcystin-LR in urban natural waters

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Autor(es):
da Silva, Jocimara Camargo ; Gomes, Wyllerson Evaristo ; Etchegaray, Augusto ; Mendes, Renata Kelly
Número total de Autores: 4
Tipo de documento: Artigo Científico
Fonte: URBAN WATER JOURNAL; v. 22, n. 4, p. 8-pg., 2025-03-10.
Resumo

Toxic cyanobacteria pose a serious threat to public health due to production of cyanotoxins, especially microcystin LR (MC-LR), which is released in water upon cell death. In humans, microcystin causes damage to the liver, affects the kidneys and is a risk to the gastrointestinal tract. In this work, MC-LR was detected using a biosensor based on alkaline phosphatase physically adsorbed on a carbon-printed electrode. The measurements were performed before and after the addition of MC-LR. The device gave linear response for a concentration range between 11 and 100 ng.L-1, in addition to high selectivity , with a limit of detection of 1.3 ng.L-1 and a limit of quantification of 4.5 ng.L-1. High accuracy was obtained, with a low relative error of 3.9% when used to quantify MC-LR in natural water. These results suggest a simple and low-cost alternative to determine if MC-LR is present in urban waters that undergo eutrophication due to high nutrient loads. (AU)

Processo FAPESP: 13/20570-6 - Produção sustentável de biossurfactantes com aplicações para medicina e remediação ambiental
Beneficiário:Augusto Etchegaray Júnior
Modalidade de apoio: Auxílio à Pesquisa - Regular