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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Periodontal disease in adults with untreated congenital growth hormone deficiency: a case-control study

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Autor(es):
Araujo Britto, Isabella M. P. [1] ; Aguiar-Oliveira, Manuel H. [2] ; Oliveira-Neto, Luiz A. [2] ; Salvatori, Roberto [3] ; Oliveira Souza, Anita H. [2] ; Araujo, Vanessa Porto [2] ; Corraini, Priscila [4, 1] ; Pannuti, Claudio Mendes [1] ; Romito, Giuseppe Alexandre [1] ; Pustiglioni, Francisco Emilio [1]
Número total de Autores: 10
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Dept Stomatol, Div Periodont, Sch Dent, BR-05508000 Sao Paulo - Brazil
[2] Univ Fed Sergipe, Div Endocrinol, Aracaju, SE - Brazil
[3] Johns Hopkins Univ, Sch Med, Div Endocrinol, Baltimore, MD - USA
[4] Aarhus Univ, Sch Dent, Dept Periodontol, Aarhus - Denmark
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF CLINICAL PERIODONTOLOGY; v. 38, n. 6, p. 525-531, JUN 2011.
Citações Web of Science: 11
Resumo

P>Aim The aim of this study was to investigate the possible associations between isolated growth hormone deficiency (IGHD) and periodontal attachment loss (PAL) in adults affected by congenital IGHD. Materials and methods Forty-five previously identified IGHD subjects were eligible for this study. The final study sample comprised 32 cases (gender:20M/12F; age:44.8 +/- 17.5) matched for age, gender, diabetes, smoking status and income to 32 controls (non-IGHD subjects). Participants were submitted to a full-mouth clinical examination of six sites per tooth and were interviewed using a structured, written questionnaire. Periodontitis was defined as proximal PAL >= 5 mm affecting >= 30% of teeth. Results No significant differences were observed in the percentage of sites with visible plaque between IGHD and non-IGHD subjects (59.4% versus 46.9%, p=0.32). IGHD subjects had significant less supragingival calculus (31.3% versus 59.4%, p=0.02) and more bleeding on probing (71.9% versus 18.8%, p < 0.01) than controls. PAL >= 5 mm was significantly more prevalent (100% versus 71.9%, p < 0.01) and affected more teeth (30.5% versus 6.7%, p < 0.01) in cases than in controls. After adjusting for supragingival calculus, IGHD cases had a higher likelihood of having periodontitis than controls (OR=17.4-17.8, 95% CI=2.3-134.9, p=0.004-0.005). Conclusion Congenital IGHD subjects have a greater chance of having PAL. (AU)

Processo FAPESP: 08/56712-0 - Perda de inserção periodontal em uma população brasileira com deficiência isolada do hormônio de crescimento: prevalência, extensão, severidade, indicadores de risco
Beneficiário:Francisco Emílio Pustiglioni
Modalidade de apoio: Auxílio à Pesquisa - Regular