| Texto completo | |
| Autor(es): |
Sousa, Vitor
;
Ludtke, Fernanda L.
;
Hijo, Ariel A. C. Toledo
;
Loureiro, Luis
;
Dias, Oscar
;
Vicente, Antonio A.
;
Pinheiro, Ana C.
;
Geada, Pedro
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | FOOD HYDROCOLLOIDS; v. 172, p. 11-pg., 2026-03-01. |
| Resumo | |
Dunaliella salina is a unicellular halophile green microalga that presents the capacity to accumulate high amounts of R-carotene, a bioactive compound widely recognized by its health benefits. To fulfil its biological functions, however, R-carotene needs to be bioaccessible, which is challenging as its bioaccessibility is typically low. A promising strategy to overcome R-carotene's low bioaccessibility is its entrapment in nanoemulsions (NEs). This study evaluated the influence of a bio-based ionic liquid (IL) as an emulsifier and different lipid concentrations on both the in vitro gastrointestinal behavior of NEs and R-carotene bioaccessibility. NEs were obtained from the sequential application of the IL as a green solvent for R-carotene extraction from D. salina and as an emulsifier to stabilize the R-carotene-loaded NEs. The NEs were composed of sunflower oil (10, 20, and 30 %), 2 % extract from D. salina enriched with R-carotene and IL and water (88, 78 and 68 %), being produced by high-intensity ultrasonication. The produced NEs were evaluated regarding physical stability (droplet size, polydispersity index, and zeta-potential) and the entrapment efficiency of R-carotene during 30 days of storage. In addition, R-carotene bioaccessibility and NEs' behavior under in vitro static digestion were evaluated as well. It was observed that the increase in lipid content resulted in higher droplet size (295-337 nm), decreased zeta-potential (-66 to-50 mV) during all the storage time, and increased R-carotene bioaccessibility (11-92 %), with no significant changes observed in R-carotene entrapment. The results suggested that the entrapment of R-carotene in NEs has great potential for its protection and for increasing its bioaccessibility. (AU) | |
| Processo FAPESP: | 22/04614-2 - Simulação da digestão de sistemas compostos por líquidos iônicos para o desenvolvimento de aditivos alimentares funcionais |
| Beneficiário: | Ariel Antonio Campos Toledo Hijo |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado |
| Processo FAPESP: | 19/18608-1 - Desenvolvimento e aplicação de líquidos iônicos derivados de compostos bioativos e de origem natural como aditivos funcionais e nutracêuticos para a indústria de alimentos |
| Beneficiário: | Ariel Antonio Campos Toledo Hijo |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |