| Texto completo | |
| Autor(es): |
Silva, Flavio Andre
;
Portes, Leslie Andrews
;
Antonio, Ednei Luiz
;
Dos Santos, Luis Felipe Neves
;
Oliveira, Helenita Antonia
;
Teixeira, Ighor Luiz Azevedo
;
Dias, Andre Rodrigues Lourenco
;
Tucci, Paulo Jose Ferreira
;
Serra, Andrey Jorge
Número total de Autores: 9
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY; v. N/A, p. 10-pg., 2025-09-18. |
| Resumo | |
Background: The cardioprotective properties of resistance training (RT) in infarcted rats have been poorly investigated. This study aimed to evaluate the effects of eight weeks of RT prior myocardial infarction (MI) in rats. Method: Groups: SSh: sedentary sham surgery; SMI: sedentary MI; TMI: trained MI. At the end of the eighth week, the animals underwent either MI or sham surgery and were analysed four weeks later. Results: The TMI presented MI sizes, scar areas, masses of the atria, right ventricle, heart, left atrial area, E wave, and E/A ratio, smaller than the SMI. The protein expression related to Ca2+ handling were not affected by the RE. The maximal load (ML) of the TMI was greater than that of the SMI group. The VO2 peak and maximum speed (Vmax) were lower in the infarcted groups. Conclusion: Prior RT confers cardioprotection against cardiac remodelling by attenuating infarct size progression, myocardial hypertrophy, and diastolic dysfunction. (AU) | |
| Processo FAPESP: | 24/09328-3 - Padrão ecocardiográfico do remodelamento cardíaco induzido pela doxorrubicina administrada por vias distintas em ratas |
| Beneficiário: | Lucas Pina Rodrigues |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 18/06865-7 - Fotobiomodulação com diodo emissor de luz (LED) pode melhorar a eficiência da terapia com células tronco mesenquimais na insuficiência cardíaca pós-infarto do miocárdio? |
| Beneficiário: | Andrey Jorge Serra |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |