| Texto completo | |
| Autor(es): |
Neri-Numa, Iramaia Angelica
;
Pessoa, Marina Gabriel
;
Arruda, Henrique Silvano
;
Pereira, Gustavo Araujo
;
Paulino, Bruno Nicolau
;
Figueiredo Angolini, Celio Fernando
;
Tasca Gois Ruiz, Ana Lucia
;
Pastore, Glaucia Maria
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Food Research International; v. 134, p. 10-pg., 2020-08-01. |
| Resumo | |
Iridoid blue-based pigments can be found in fruits of genipap (Genipa americana L.). Besides being a potential source of natural blue colorant in the food industry, they have also been associated with pharmacological effects. Therefore, the recovery of iridoids by ultrasound-assisted extraction from both unripe and ripe fruits was analysed by UPLC-DAD-ESI-(-)-QTOF-MS/MS. Nine iridoids were identified from their exact masses and fragmentation pattern, namely geniposidic acid, gardenoside, genipin-1-beta-gentiobioside, geniposide, 6 ''-O-p-coumaroyl-1-beta-gentiobioside geniposidic acid, 6 ''-O-p-coumaroylgenipin-gentiobioside, genipin, 6 '-O-p-coumaroyl-geniposidic acid and 6 '-O-feruloyl-geniposidic acid. Among them, genipin (60.77 mg/g fdw) was found to be the most abundant iridoid in unripe genipap extract, while the ripe genipap extract mainly contained geniposide and geniposidic acid (89.48 and 25.04 mg/g fdw, respectively). It was also observed that the iridoids of the unripe genipap extract are able to scavenger DPPH, ABTS and peroxyl radicals as well as exerting a cytostatic effect against both glioma and breast cancer cell lines. This study provided information about the properties of unripe and ripe genipap extracts which can be used as a reference for further studies focusing on the potential application of G. americana L. in commercial products containing natural blue colorant with functional claims. (AU) | |
| Processo FAPESP: | 15/50333-1 - Cobra: nova plataforma de descoberta de compostos para identificação rápida e de baixo custo de bioativo com efeitos benéficos originários de plantas brasileiras |
| Beneficiário: | Glaucia Maria Pastore |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |