| Texto completo | |
| Autor(es): Mostrar menos - |
de Paiva, Joao Paulo Goncalves
;
Sousa-Neto, Sebastiao Silverio
;
Humberto, Maurilo Antonio Correia
;
Magalhaes, Marco Antonio de Oliveira
;
Bubola, Justin
;
Assuncao Jr, Jose Narciso Rosa
;
Marcucci, Marcelo
;
Sena-Filho, Marcondes
;
Lemos, Celso Augusto
;
Saldivia-Siracusa, Cristina
;
Santos-Silva, Alan Roger
;
Jorge, Jacks
;
Vargas, Pablo Agustin
Número total de Autores: 13
|
| Tipo de documento: | Artigo Científico |
| Fonte: | SPECIAL CARE IN DENTISTRY; v. 45, n. 6, p. 12-pg., 2025-11-01. |
| Resumo | |
Aims: The aim of this study is to characterize the clinical and microscopic features of recurrent oral/labial HSV-1 infection with unusual clinical presentations. Methods: A literature review and retrospective case series of patients with recurrent oral/labial HSV-1 with unusual presentations were conducted. Data were collected from medical records, and all cases were confirmed by histopathology and immunohistochemistry. Results: Eight patients (five males, 62.5%; three females, 37.5%) with a mean age of 61.8 years presented with unusual HSV-1 manifestations, including solitary lesions, white plaque-like appearance, non-keratinized site involvement, or prolonged duration. Lesions involved the tongue border (n = 4, 50%), anterior ventral tongue, hard palate, posterior ridge crest, and lower lip (n = 1, 12.5% each). Presented as well-demarcated solitary ulcers (n = 6, 75%), solitary papule (n = 1, 12.5%), and whitish plaque-like lesions (n = 1, 12.5%). Only two patients were immunosuppressed. All cases responded successfully to management, including pharmacotherapy, surgical excision, or photobiomodulation. Unusual clinical presentations of oral/labial HSV-1 infection are scarcely reported in the literature. Conclusion: Unusual HSV-1 manifestations can occur in immunocompetent individuals; however, exclusion of undiagnosed immunosuppression remains necessary. A definitive diagnosis relies on careful histopathological evaluation of ulcer edges, which is crucial for guiding appropriate treatment. Further documentation of similar cases is essential to reinforce that these unusual presentations can indeed affect immunocompetent patients. (AU) | |
| Processo FAPESP: | 23/13797-6 - Estratégias de quimioterapia direcionada para a eliminação das celulas-tronco tumorais em pacientes jovens com carcinoma espinocelular oral |
| Beneficiário: | Sebastião Silvério de Sousa Neto |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |