High-Intensity Laser and Photodynamic Therapy as a Treatment for Recurrent Herpes Labialis

Autor(es)

Marotti, Juliana ^[1] ; Sperandio, Felipe Fornias ^[2] ; Fregnani, Eduardo Rodrigues ^[3] ; Correa Aranha, Ana Cecilia ^[4] ; de Freitas, Patricia Moreira ^[4] ; Eduardo, Carlos de Paula ^[4]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Special Lab Lasers Dent LELO, Sch Dent, Dept Prosthodont, BR-05508000 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Special Lab Lasers Dent LELO, Sch Dent, Dept Oral Pathol, BR-05508000 Sao Paulo - Brazil

^[3] AC Camargo Hosp, Dept Stomatol, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Special Lab Lasers Dent LELO, Dept Restorat Dent, Sch Dent, BR-05508000 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Photomedicine and Laser Surgery; v. 28, n. 3, p. 439-444, JUN 2010.
• Citações Web of Science: 21

Resumo

Objective: The aim of this study was to report the treatment of recurrent herpes labialis (RHL) using a high-intensity laser or methylene blue (MB)-mediated photodynamic therapy (PDT) in combination with low-level laser therapy (LLLT). Materials and Methods: Four clinical cases of patients diagnosed with RHL are described in this report. Two patients were subjected to high-intensity laser therapy (HILT) followed by LLLT, and two patients received MB-mediated PDT, again followed by LLLT. LLLT was conducted at 24, 48, 72 h, and 7 d after HILT or PDT. Patients were followed up after 6 mo. Results: Throughout the follow-up period, all patients reported pain relief and did not show any signs or symptoms of RHL. A favorable healing process was observed in all cases. None of the patients reported pain as a consequence of the treatment. Conclusion: These results suggest that HILT and MB-mediated PDT, in combination with LLLT, may constitute a benefit when treating vesicles in RHL. (AU)

• Processo FAPESP: 98/14270-8 - Centro de Ciências Ópticas e Fotônica
• Beneficiário: Vanderlei Salvador Bagnato
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs