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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

High-Intensity Laser and Photodynamic Therapy as a Treatment for Recurrent Herpes Labialis

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Author(s):
Marotti, Juliana [1] ; Sperandio, Felipe Fornias [2] ; Fregnani, Eduardo Rodrigues [3] ; Correa Aranha, Ana Cecilia [4] ; de Freitas, Patricia Moreira [4] ; Eduardo, Carlos de Paula [4]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Special Lab Lasers Dent LELO, Sch Dent, Dept Prosthodont, BR-05508000 Sao Paulo - Brazil
[2] Univ Sao Paulo, Special Lab Lasers Dent LELO, Sch Dent, Dept Oral Pathol, BR-05508000 Sao Paulo - Brazil
[3] AC Camargo Hosp, Dept Stomatol, Sao Paulo - Brazil
[4] Univ Sao Paulo, Special Lab Lasers Dent LELO, Dept Restorat Dent, Sch Dent, BR-05508000 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Photomedicine and Laser Surgery; v. 28, n. 3, p. 439-444, JUN 2010.
Web of Science Citations: 21
Abstract

Objective: The aim of this study was to report the treatment of recurrent herpes labialis (RHL) using a high-intensity laser or methylene blue (MB)-mediated photodynamic therapy (PDT) in combination with low-level laser therapy (LLLT). Materials and Methods: Four clinical cases of patients diagnosed with RHL are described in this report. Two patients were subjected to high-intensity laser therapy (HILT) followed by LLLT, and two patients received MB-mediated PDT, again followed by LLLT. LLLT was conducted at 24, 48, 72 h, and 7 d after HILT or PDT. Patients were followed up after 6 mo. Results: Throughout the follow-up period, all patients reported pain relief and did not show any signs or symptoms of RHL. A favorable healing process was observed in all cases. None of the patients reported pain as a consequence of the treatment. Conclusion: These results suggest that HILT and MB-mediated PDT, in combination with LLLT, may constitute a benefit when treating vesicles in RHL. (AU)

FAPESP's process: 98/14270-8 - Center for Optical and Photonics Science
Grantee:Vanderlei Salvador Bagnato
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC