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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

A Community-based Survey of Human Toxoplasmosis in Rural Amazonia: Seroprevalence, Seroconversion Rate, and Associated Risk Factors

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Autor(es):
Ferreira, Marcelo U. [1] ; Hiramoto, Roberto M. [2] ; Aureliano, Debora P. [2] ; da Silva-Nunes, Monica [1, 3] ; da Silva, Natal S. [1] ; Malafronte, Rosely S. [4] ; Muniz, Pascoal T. [3]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Biomed Sci, Dept Parasitol, BR-05508900 Sao Paulo - Brazil
[2] Adolfo Lutz Inst, Sect Syst Parasit Dis, BR-01246000 Sao Paulo - Brazil
[3] Univ Fed Acre, Dept Hlth Sci, BR-69915900 Rio Branco, AC - Brazil
[4] Inst Trop Med Sao Paulo, BR-05403000 Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: American Journal of Tropical Medicine and Hygiene; v. 81, n. 1, p. 171-176, JUL 2009.
Citações Web of Science: 10
Resumo

IgG antibodies to Toxoplasma gondii were detected in, March-April 2004, in 65.8% (95% confidence interval, 60.8-70.8%) of 342 systematically sampled subjects 5-90 years of age (87.5% of the eligible) living in a rural settlement in Amazonia, with a seroconversion rate of 9% over I year of follow-up of 99 seronegative subjects. Multiple logistic regression analysis identified age as the only significant independent predictor of seropositivity at the baseline. Each additional year of age increases the odds of being seropositive by 6%, and 76.8% of the subjects are expected to be seropositive at 30 years of age. A single high-prevalence spatial cluster, comprising 11.9% of the seropositive subjects, was detected in the area; households in the cluster were less likely to have dogs as pets and their heads had a lower education level, when compared with households located outside the cluster. The challenges for preventing human toxoplasmosis in tropical rural settings are discussed. (AU)

Processo FAPESP: 05/51988-0 - Epidemiologia da malaria: fatores de risco, distribuicao espaco-temporal e resposta ao tratamento em uma coorte rural amazonica.
Beneficiário:Marcelo Urbano Ferreira
Modalidade de apoio: Auxílio à Pesquisa - Regular