Antioxidant activity and physical-chemical properties of spray and spouted bed dried extracts of Bauhinia forficata

Autor(es)

Fernandes Souza, Claudia Regina ^[1] ; Georgetti, Sandra Regina ^[2] ; Salvador, Marcos Jose ^[3] ; Vieira Fonseca, Maria Jose ^[1] ; Oliveira, Wanderley Pereira ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dept Pharmaceut Sci, Fac Pharmaceut Sci Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil

^[2] Univ Estadual Londrina, Dept Food & Drugs Technol, Hlth Sci Ctr, Londrina, Parana - Brazil

^[3] Univ Estadual Campinas, Inst Biol, Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Brazilian Journal of Pharmaceutical Sciences; v. 45, n. 2, p. 209-218, APR-JUN 2009.
• Citações Web of Science: 4

Resumo

Two distinct drying methods (spouted bed and spray drying) were used for production of dried extracts of Bauhinia forficata Link (Leguminosae, Caesalpinoideae). High-quality powder products in terms of physical and chemical properties were obtained. HPLC fingerprints revealed that the chromatographic profiles of flavonoid compounds present in the dried extract did not change significantly, due to drying. In general, the spouted bed drying caused a degradation of total flavonoids than was lower than that of the spray drying. Antioxidant properties of the dried extract, examined by their radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl radical (DPPH•) and inhibition of lipid peroxidation induced by Fe+2 assays (LPO), confirmed their antioxidant potential. The slight reduction in scavenging activity of the dried extracts may be associated with the occurrence of oxidative reactions, decomposition or losses of thermolabile compounds, induced by the heat. (AU)

• Processo FAPESP: 01/10140-7 - Extratos secos padronizados de plantas medicinais: analise comparativa entre processos de producao e avaliacao de propriedades fisico quimicas e da estabilidade do produto.
• Beneficiário: Wanderley Pereira Oliveira
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 03/08317-1 - Produção de extratos secos padronizados de plantas medicinais brasileiras: estudo da viabilidade técnica e econômica do processo leito de jorro
• Beneficiário: Cláudia Regina Fernandes de Souza
• Modalidade de apoio: Bolsas no Brasil - Doutorado