Influence of genotype on dopamine transporter availability in human striatum and sleep architecture

Autor(es)

Guindalini, Camila ^{[1, 2]} ; Martins, Raquel Cristina ^[1] ; Andersen, Monica L. ^[1] ; Tufik, Sergio ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Dept Psychobiol, Escola Paulista Med, BR-04021002 Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Psychiat, Escola Paulista Med, LiNC, BR-04021002 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: PSYCHIATRY RESEARCH; v. 179, n. 2, p. 238-240, SEP 30 2010.
• Citações Web of Science: 7

Resumo

Genetic variants may modulate dopamine transporter (DAT) availability in the brain. A polymorphism within the intron 8 of the DAT1 gene was evaluated in 27 healthy men. No correlation between Int8 VNTR and either the inter-individual variability of the sleep architecture, or the DAT availability, as measured by single photon emission computed tomography (SPECT) and {[}(99m)Tc]TRODAT-1 was observed. (C) 2009 Elsevier Ireland Ltd. All rights reserved. (AU)

• Processo FAPESP: 98/14303-3 - Center for Sleep Studies
• Beneficiário: Sergio Tufik
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs