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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The relationship between sleep and epilepsy: Evidence from clinical trials and animal models

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Autor(es):
Matos, Gabriela [1] ; Andersen, Monica L. [2] ; do Valle, Angela Cristina [1] ; Tufik, Sergio [2]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Dept Pathol, Fac Med, BR-01246903 Sao Paulo - Brazil
[2] Univ Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo de Revisão
Fonte: JOURNAL OF THE NEUROLOGICAL SCIENCES; v. 295, n. 1-2, p. 1-7, AUG 15 2010.
Citações Web of Science: 42
Resumo

Interactions between sleep and epilepsy have been widely documented. Sleep can modulate epileptic phenomena, and epilepsy and seizures disorganize the macro- and micro-architecture of sleep. In turn, sleep deprivation exerts a strong influence on the occurrence of seizures and interictal epileptiform discharges. Recently, sleep disturbances occurring in conjunction with epilepsy have been suggested to lead to a worsening of the quality of life for patients with epilepsy. In addition, data from animal models clarify many gaps in this relationship. In this brief review, we present an outline of the interactions between sleep and epilepsy based on a thorough review of the existing literature. (C) 2010 Elsevier B.V. All rights reserved. (AU)

Processo FAPESP: 98/14303-3 - Center for Sleep Studies
Beneficiário:Sergio Tufik
Linha de fomento: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs