Type of Alcoholic Beverage and Risk of Head and Neck Cancer-025EFA Pooled Analysis Within the INHANCE Consortium

Autor(es):Mostrar menos -

Purdue, Mark P. ^[1] ; Hashibe, Mia ^[2] ; Berthiller, Julien ^[2] ; La Vecchia, Carlo ^{[3, 4]} ; Dal Maso, Luigino ^[5] ; Herrero, Rolando ^[6] ; Franceschi, Silvia ^[2] ; Castellsague, Xavier ^[7] ; Wei, Qingyi ^[8] ; Sturgis, Erich M. ^[8] ; Morgenstern, Hal ^[9] ; Zhang, Zuo-Feng ^[10] ; Levi, Fabio ^[11] ; Talamini, Renato ^[5] ; Smith, Elaine ^[12] ; Muscat, Joshua ^[13] ; Lazarus, Philip ^[13] ; Schwartz, Stephen M. ^[14] ; Chen, Chu ^[14] ; Eluf Neto, Jose ^[15] ; Wuensch-Filho, Victor ^[15] ; Zaridze, David ^[16] ; Koifman, Sergio ^[17] ; Curado, Maria Paula ^[2] ; Benhamou, Simone ^[18] ; Matos, Elena ^[19] ; Szeszenia-Dabrowska, Neonilia ^[20] ; Olshan, Andrew F. ^[21] ; Lence, Juan ^[22] ; Menezes, Ana ^[23] ; Daudt, Alexander W. ^[24] ; Mates, Ioan Nicolae ^[25] ; Pilarska, Agnieszka ^[26] ; Fabianova, Eleonora ^[27] ; Rudnai, Peter ^[28] ; Winn, Debbie ^[1] ; Ferro, Gilles ^[2] ; Brennan, Paul ^[2] ; Boffetta, Paolo ^[2] ; Hayes, Richard B. ^[1]

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^[1] NCI, Rockville, MD 20852 - USA

^[2] Int Agcy Res Canc, F-69372 Lyon - France

^[3] Univ Milan, Milan - Italy

^[4] Ist Ric Farmacol Mario Negri, Milan - Italy

^[5] Aviano Canc Ctr, I-33081 Aviano - Italy

^[6] Inst Invest Epidemiol, San Jose - Costa Rica

^[7] Inst Catala Oncol, Barcelona - Spain

^[8] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 - USA

^[9] Univ Michigan, Sch Publ Hlth, Ann Arbor, MI 48109 - USA

^[10] Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 - USA

^[11] Inst Univ Med Sociale & Prevent, CH-1005 Lausanne - Switzerland

^[12] Univ Iowa, Coll Publ Hlth, Iowa City, IA - USA

^[13] Penn State Coll Med, Hershey, PA - USA

^[14] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 - USA

^[15] Univ Sao Paulo, Sao Paulo - Brazil

^[16] Russian Acad Med Sci, Canc Res Ctr, Moscow - Russia

^[17] Escola Nacl Suade Publ, Rio De Janeiro - Brazil

^[18] INSERM, U794, Evry - France

^[19] Univ Buenos Aires, Inst Oncol Angel H Roffo, Buenos Aires, DF - Argentina

^[20] Inst Occupat Med, Lodz - Poland

^[21] Univ N Carolina, Sch Publ Hlth, Chapel Hill, NC - USA

^[22] Inst Oncol & Radiobiol, Havana - Cuba

^[23] Univ Fed Pelotas, Pelotas - Brazil

^[24] Hosp Clin Porto Alegre, Porto Alegre, RS - Brazil

^[25] Univ Carol Davila, Fac Med, Bucharest - Romania

^[26] Med Acad, Maxillofacial Surg Clin 2, Warsaw - Poland

^[27] Specialized State Hlth Inst, Banska Bystrica - Slovakia

^[28] Natl Inst Environm Hlth, Budapest - Hungary

• Tipo de documento: Artigo Científico
• Fonte: AMERICAN JOURNAL OF EPIDEMIOLOGY; v. 169, n. 2, p. 132-142, JAN 15 2009.
• Citações Web of Science: 53

Resumo

The authors pooled data from 15 case-control studies of head and neck cancer (9,107 cases, 14,219 controls) to investigate the independent associations with consumption of beer, wine, and liquor. In particular, they calculated associations with different measures of beverage consumption separately for subjects who drank beer only (858 cases, 986 controls), for liquor-only drinkers (499 cases, 527 controls), and for wine-only drinkers (1,021 cases, 2,460 controls), with alcohol never drinkers (1,124 cases, 3,487 controls) used as a common reference group. The authors observed similar associations with ethanol-standardized consumption frequency for beer-only drinkers (odds ratios (ORs) = 1.6, 1.9, 2.2, and 5.4 for <= 5, 6-15, 16-30, and > 30 drinks per week, respectively; P(trend) < 0.0001) and liquor-only drinkers (ORs = 1.6, 1.5, 2.3, and 3.6; P < 0.0001). Among wine-only drinkers, the odds ratios for moderate levels of consumption frequency approached the null, whereas those for higher consumption levels were comparable to those of drinkers of other beverage types (ORs = 1.1, 1.2, 1.9, and 6.3; P < 0.0001). Study findings suggest that the relative risks of head and neck cancer for beer and liquor are comparable. The authors observed weaker associations with moderate wine consumption, although they cannot rule out confounding from diet and other lifestyle factors as an explanation for this finding. Given the presence of heterogeneity in study-specific results, their findings should be interpreted with caution. (AU)

• Processo FAPESP: 01/01768-2 - Estudo internacional de fatores ambientais, vírus e câncer de cavidade oral e de laringe
• Beneficiário: José Eluf Neto
• Modalidade de apoio: Auxílio à Pesquisa - Regular