Employing Genetic Markers to Improve Diagnosis of Thyroid Tumor Fine Needle Biopsy

Autor(es)

Cerutti, Janete M. ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Genet Bases Thyroid Tumor Lab, Dept Morphol & Genet, Div Genet, BR-04039032 Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Med, Div Endocrinol, BR-04039032 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: CURRENT GENOMICS; v. 12, n. 8, p. 589-596, DEC 2011.
• Citações Web of Science: 11

Resumo

Fine-Needle Aspiration (FNA) is the most widely used and cost-effective preoperative test for the initial evaluation of a thyroid nodule, although it has limited diagnostic accuracy for several types of tumors. Patients will often receive cytological report of indeterminate cytology and are referred to surgery for a more accurate diagnosis. An improved test would help physicians rapidly focus treatment on true malignancies and avoid some unnecessary treatment of benign tumors. This review will discuss current molecular markers that may improve thyroid nodule diagnosis. (AU)

• Processo FAPESP: 05/60330-8 - Marcadores moleculares no diagnóstico e prognóstico de pacientes com tumores da tiroide humana: transição da pesquisa básica para a clínica
• Beneficiário: Janete Maria Cerutti
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 09/11257-7 - Análise do Papel da Arginase II (ARG2) na Patogênese dos Tumores da Tiróide
• Beneficiário: Janete Maria Cerutti
• Modalidade de apoio: Auxílio à Pesquisa - Regular