In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi

Autor(es)

Goncalves, Sarah S. ^[1] ; Stchigel, Alberto M. ^[2] ; Cano, Josep ^[2] ; Guarro, Josep ^[2] ; Colombo, Arnaldo L. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Dept Med, Special Mycol Lab LEMI, Sao Paulo - Brazil

^[2] Univ Rovira & Virgili, Sch Med, IISPV, Mycol Unit, E-43201 Reus - Spain

• Tipo de documento: Artigo Científico
• Fonte: Antimicrobial Agents and Chemotherapy; v. 57, n. 4, p. 1944-1947, APR 2013.
• Citações Web of Science: 20

Resumo

The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A. flavus, was tested for nine antifungal agents using a microdilution reference method (CLSI, M38-A2). Terbinafine and the echinocandins demonstrated lower MICs/MECs for all species evaluated, followed by posaconazole. Amphotericin B showed MICs >= 2 mu g/ml for 38 (49.4%) of the 77 isolates tested. (AU)

• Processo FAPESP: 12/01134-8 - Prevalência de espécies de Aspergillus em amostras de origem clínica/ambiental e análise de seu perfil de susceptibilidade a 6 antifúngicos
• Beneficiário: Arnaldo Lopes Colombo
• Modalidade de apoio: Auxílio à Pesquisa - Regular