Monitoring chronic physical stress using biomarkers, performance protocols and mathematical functions to identify physiological adaptations in rats

Autor(es)

de Araujo, Gustavo Gomes ^{[1, 2]} ; Papoti, Marcelo ^[3] ; Manchado-Gobatto, Fulvia de Barros ^[1] ; Rostom de Mello, Maria Alice ^[4] ; Gobatto, Claudio Alexandre ^[1]

Afiliação do(s) autor(es)

^[1] Campinas State Univ UNICAMP, Lab Sports Appl Physiol, BR-13484350 Limeira, SP - Brazil

^[2] Fed Univ Alagoas UFAL, Sports Sci Res Grp, BR-57072970 Maceio, Alagoas - Brazil

^[3] Univ Sao Paulo, BR-14040900 Ribeirao Preto, SP - Brazil

^[4] Sao Paulo State Univ UNESP, BR-13505900 Rio Claro, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: LABORATORY ANIMALS; v. 47, n. 1, p. 36-42, JAN 2013.
• Citações Web of Science: 7

Resumo

This study was undertaken to characterize the effects of monotonous training at lactate minimum (LM) intensity on aerobic and anaerobic performances; glycogen concentrations in the soleus muscle, the gastrocnemius muscle and the liver; and creatine kinase (CK), free fatty acids and glucose concentrations in rats. The rats were separated into trained (n = 10), baseline (n = 10) and sedentary (n = 10) groups. The trained group was submitted to the following: 60 min/day, 6 day/week and intensity equivalent to LM during the 12-week training period. The training volume was reduced after four weeks according to a sigmoid function. The total CK (U/L) increased in the trained group after 12 weeks (742.0 +/- 158.5) in comparison with the baseline (319.6 +/- 40.2) and the sedentary (261.6 +/- 42.2) groups. Free fatty acids and glycogen stores (liver, soleus muscle and gastrocnemius muscle) increased after 12 weeks of monotonous training but aerobic and anaerobic performances were unchanged in relation to the sedentary group. The monotonous training at LM increased the level of energy substrates, unchanged aerobic performance, reduced anaerobic capacity and increased the serum CK concentration; however, the rats did not achieve the predicted training volume. (AU)

• Processo FAPESP: 06/58411-2 - Efeitos de quatro modelos de treinamento experimental de natação sobre biomarcadores de adaptação e capacidades aeróbia e anaeróbia em ratos Wistar
• Beneficiário: Gustavo Gomes de Araujo
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 04/07070-5 - Protocolos invasivos e nao invasivos para avaliacao aerobia e anaerobia de ratos wistar.
• Beneficiário: Fúlvia de Barros Manchado Gobatto
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 04/01205-6 - Padronizacao de um protocolo experimental de treinamento periodizado em natacao, utilizando ratos wistar.
• Beneficiário: Gustavo Gomes de Araujo
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica