Clinical and microbiological changes after minimally invasive therapeutic approaches in intrabony defects: a 12-month follow-up

Autor(es)

Ribeiro, Fernanda V. ^[1] ; Casarin, Renato C. V. ^[1] ; Palma, Maria A. G. ^[2] ; Junior, Francisco H. N. ^[2] ; Sallum, Enilson A. ^[2] ; Casati, Marcio Z. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista, Sch Dent, Dent Res Div, Sao Paulo - Brazil

^[2] Univ Campinas UNICAMP, Sch Dent Piracicaba, Dept Prosthodont & Periodont, BR-13414903 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: CLINICAL ORAL INVESTIGATIONS; v. 17, n. 7, p. 1635-1644, SEP 2013.
• Citações Web of Science: 0

Resumo

This 12-month randomized, controlled trial evaluated the clinical effects and microbiological changes of minimally invasive nonsurgical and surgical approaches for the therapy of intrabony defects. Twenty-nine subjects with intrabony defects in single-rooted tooth were randomly assigned to; (1) minimally invasive nonsurgical technique (MINST) or (2) minimally invasive surgical technique (MIST). Quantities of Aggregatibacter actinomycetemcomitans, Tannerella forsythia, and Porphyromonas gingivalis, determined by using real-time PCR, were evaluated at baseline, 3, 6, and 12 months after the treatments. Clinical recordings-probing depth (PD), position of the gingival margin (PGM), and relative clinical attachment level (RCAL)-were obtained at baseline and 12 months post-therapy. The primary outcome variable of the study was RCAL. Both treatment modalities resulted in an improvement in all clinical recordings, with significant PD reductions (p < 0.05), RCAL gains (p < 0.05), and no change in the PGM (p > 0.05) after 12 months in both MINST and MIST groups. No clinical differences were observed between groups (p > 0.05). Regarding the microbiological outcomes, at the re-examinations, a significant decrease was observed for T. forsythia and P. gingivalis when compared with baseline (p < 0.05) for both treatments. The amount of A. actinomycetemcomitans did not reduced decrease throughout the study (p > 0.05). Intergroup differences in the microbiological assay were not found at any time point (p > 0.05). Both MINST and MIST provided comparable clinical results and microbiological changes in the treatment of intrabony defects over 12 months follow-up. This randomized, controlled, parallel trial revealed that both therapeutic modalities may promote clinical and microbiological benefits at 12 months post-therapy. (AU)

• Processo FAPESP: 08/50027-4 - Avaliação clínica, imunoenzimática e microbiológica na periodontia: do tratamento da doença à regeneração dos defeitos periodontais
• Beneficiário: Márcio Zaffalon Casati
• Modalidade de apoio: Auxílio à Pesquisa - Regular