Automatic lumen segmentation in IVOCT images using binary morphological reconstruction

Autor(es)

Moraes, Matheus Cardoso ^[1] ; Cardona Cardenas, Diego Armando ^[1] ; Furuie, Sergio Shiguemi ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Engn, Dept Telecommun & Control, BR-05508970 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BIOMEDICAL ENGINEERING ONLINE; v. 12, AUG 9 2013.
• Citações Web of Science: 13

Resumo

Background: Atherosclerosis causes millions of deaths, annually yielding billions in expenses round the world. Intravascular Optical Coherence Tomography (IVOCT) is a medical imaging modality, which displays high resolution images of coronary cross-section. Nonetheless, quantitative information can only be obtained with segmentation; consequently, more adequate diagnostics, therapies and interventions can be provided. Since it is a relatively new modality, many different segmentation methods, available in the literature for other modalities, could be successfully applied to IVOCT images, improving accuracies and uses. Method: An automatic lumen segmentation approach, based on Wavelet Transform and Mathematical Morphology, is presented. The methodology is divided into three main parts. First, the preprocessing stage attenuates and enhances undesirable and important information, respectively. Second, in the feature extraction block, wavelet is associated with an adapted version of Otsu threshold; hence, tissue information is discriminated and binarized. Finally, binary morphological reconstruction improves the binary information and constructs the binary lumen object. Results: The evaluation was carried out by segmenting 290 challenging images from human and pig coronaries, and rabbit iliac arteries; the outcomes were compared with the gold standards made by experts. The resultant accuracy was obtained: True Positive (%) = 99.29 +/- 2.96, False Positive (%) = 3.69 +/- 2.88, False Negative (%) = 0.71 +/- 2.96, Max False Positive Distance (mm) = 0.1 +/- 0.07, Max False Negative Distance (mm) = 0.06 +/- 0.1. Conclusions: In conclusion, by segmenting a number of IVOCT images with various features, the proposed technique showed to be robust and more accurate than published studies; in addition, the method is completely automatic, providing a new tool for IVOCT segmentation. (AU)

• Processo FAPESP: 12/15721-2 - Investigação de lesões ateroscleróticas por ultrassom e tomografia óptica
• Beneficiário: Matheus Cardoso Moraes
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado