The effect of mate tea (Ilex paraguariensis) on metabolic and inflammatory parameters in high-fat diet-fed Wistar rats

Autor(es)

Borges, Maria Carolina ^[1] ; Ramirez Vinolo, Marco Aurelio ^[2] ; Nakajima, Karina ^[3] ; De Castro, Inar Alvesde ^[4] ; Markowicz Bastos, Deborah Helena ^[1] ; Borelli, Primavera ^[3] ; Fock, Ricardo Ambrosio ^[3] ; Tirapegui, Julio ^[4] ; Curi, Rui ^[2] ; Rogero, Marcelo Macedo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, BR-01246904 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, BR-05508000 Sao Paulo - Brazil

^[3] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Clin & Toxicol Anal, BR-05508000 Sao Paulo - Brazil

^[4] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Food & Expt Nutr, BR-05508000 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION; v. 64, n. 5, p. 561-569, AUG 2013.
• Citações Web of Science: 14

Resumo

This study investigated the effects of mate tea (Ilex paraguariensis) aqueous extract consumption on metabolic indicators and inflammatory response of peritoneal macrophages in rats fed a high-fat diet (HFD). Male Wistar rats were fed a control diet or a HFD for 12 weeks. At the end of this period, rats received, or not, daily doses of yerba mate for 4 weeks. The consumption of yerba mate promoted weight loss, attenuated the HFD-detrimental effects on adiposity and insulin sensitivity and decreased blood levels of the inflammatory biomarkers (p < 0.05). Concerning peritoneal macrophages, mate tea consumption decreased the production of interleukin (IL)-6, but did not influence the production of IL-1 beta, tumour necrosis factor-a and nitric oxide; cytokine mRNA expression; or the activation of the nuclear factor-kappa B signalling pathway. In summary, the consumption of mate tea had no consistent effect in the inflammatory response of peritoneal macrophages, but reduced cardiometabolic risk markers. (AU)

• Processo FAPESP: 09/02371-0 - Efeito da ingestão do extrato aquoso de erva-mate (Ilex paraguariensis) sobre a via de sinalização do fator nuclear kappa B de macrófagos peritoniais de ratos submetidos à dieta hiperlipídica
• Beneficiário: Maria Carolina Borges
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 09/50269-0 - Efeito da ingestão do extrato aquoso de erva-mate (Ilex paraguariensis) sobre a via de sinalização do fator nuclear kappa B de macrófagos peritoniais de ratos submetidos à dieta hiperlipídica
• Beneficiário: Marcelo Macedo Rogero
• Modalidade de apoio: Auxílio à Pesquisa - Regular