Excess iodinuria in infants and its relation to the iodine in maternal milk

Autor(es)

de Lima, Livia Fernandes ^[1] ; Barbosa Junior, Fernando ^{[2, 3]} ; Navarro, Anderson Marliere ^[1]

Afiliação do(s) autor(es)

^[1] Fac Med Ribeirao Preto, Dept Internal Med, BR-14049900 Ribeirao Preto, SP - Brazil

^[2] Fac Pharm Ribeirao Preto, Dept Clin Toxicol & Bromatol Anal, Lab Toxicol & Met Essential, Ribeirao Preto, SP - Brazil

^[3] Fac Pharm Ribeirao Preto, Dept Clin Toxicol & Bromatol Anal, BR-14049903 Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY; v. 27, n. 3, p. 221-225, 2013.
• Citações Web of Science: 8

Resumo

Objective: Iodine is an essential micro nutrient, and a deficiency or excessive intake of this mineral is related to changes in thyroid function. In Brazil, both deficiency and excessive intake of iodine are common; however, excessive intakes have recently been observed. Thus, the objective of the present study was to assess the iodine concentration in maternal milk, taking into account the salt iodine concentration of the participating households and in the infants' urine. Method: Urine samples from 33 infants (less than 6 months of age), maternal milk samples and samples of the kitchen salt used by the mothers were collected. The iodine levels in the urine and maternal milk were assessed by ICP-MS; the iodine levels in the salt were assessed by titration. Result: The median iodinuria value in the infants was 293 mu g/L; the mean iodine concentration was 206 mu g/L in the maternal milk and 39.9 mg I/kg in the salt. There was a positive correlation between the iodine concentration in the maternal milk and the infant iodinuria value. Conclusion: The median infant iodinuria was elevated due to the high iodine concentration present in the maternal milk. High iodine values were caused by high salt iodine levels, which should be reduced. (C) 2013 Elsevier GmbH. All rights reserved. (AU)

• Processo FAPESP: 09/15190-4 - Avaliação da excreção urinária de iodo em lactentes
• Beneficiário: Livia Fernandes de Lima
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica