1,1-Diamino-2-nitroethylenes as excellent hydrogen bond donor organocatalysts in the Michael addition of carbon-based nucleophiles to beta-nitrostyrenes

Autor(es)

da Silva, Rodrigo C. ^[1] ; da Silva, Gustavo P. ^[1] ; Sangi, Diego P. ^{[2, 1]} ; Pontes, Joao G. de M. ^[1] ; Ferreira, Antonio G. ^[1] ; Correa, Arlene G. ^[1] ; Paixao, Marcio W. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Carlos, Dept Quim, BR-13560 Sao Carlos, SP - Brazil

^[2] Univ Fed Fluminense, Inst Ciencias Exatas, BR-27213145 Volta Redonda, RJ - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Tetrahedron; v. 69, n. 43, p. 9007-9012, OCT 28 2013.
• Citações Web of Science: 8

Resumo

A new class of hydrogen bond donor catalysts based on the 1,1-diamino-2-nitreethylene scaffold has been introduced for the activation of trans-beta-nitrostyrenes toward reactions with a range of carbon-based nucleophiles, affording the corresponding adducts in excellent yields. Importantly, this new set of organocatalysts is easily prepared from commercially available starting materials in mild reaction conditions. (C) 2013 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 09/07281-0 - Organocatálise assimétrica: preparação de novos organocatalisadores e desenvolvimento de novas metodologias
• Beneficiário: Márcio Weber Paixão
• Linha de fomento: Auxílio à Pesquisa - Apoio a Jovens Pesquisadores