Structural and morphological investigations of beta-cyclodextrin-coated silver nanoparticles

Autor(es)

Andrade, Patricia Fernanda ^[1] ; de Faria, Andreia Fonseca ^[1] ; da Silva, Douglas Soares ^[1] ; Bonacin, Juliano Alves ^[1] ; Goncalves, Maria do Carmo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, UNICAMP, Inst Chem, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: COLLOIDS AND SURFACES B-BIOINTERFACES; v. 118, p. 289-297, JUN 1 2014.
• Citações Web of Science: 21

Resumo

This paper describes the synthesis of silver nanoparticles using an aqueous silver nitrate solution in the presence of glucose as a reducing agent, sodium hydroxide as a reaction catalyst and beta-CD as a stabilizer. The structure and the morphology associated to the stabilizing layer around the silver nanoparticles were investigated. Raman spectroscopy confirmed the nanoparticle surface modification by beta-CD, demonstrating the interaction between the beta-CD rim hydroxyl groups and the AgNP surface. Transmission electron microscopy images showed an average 28.0 nm diameter pseudo-spherical nanoparticles. Apart from this, a novel characterization of the beta-CD layer surrounding the nanoparticles was carried out by using complementary analytical electron microscopy based on electron spectroscopy imaging in the transmission microscope. Mapping images revealed the presence of carbon and oxygen, demonstrating the existence of a uniform and interacting beta-CD layer covering the nanoparticles. The antibacterial activity was also investigated and the beta-CD-coated silver nanoparticles showed a promising bactericidal activity against the microorganism Escherichia coli. (C) 2014 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 10/17804-7 - Compósitos poliméricos
• Beneficiário: Maria Isabel Felisberti
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 08/57867-8 - Instituto Nacional de Ciência, Tecnologia e Inovação em Materiais Complexos Funcionais (INOMAT)
• Beneficiário: Fernando Galembeck
• Modalidade de apoio: Auxílio à Pesquisa - Temático