Synthesis of polyHEMA hydrogels for using as biomaterials. Bulk and solution radical-initiated polymerization techniques

Autor(es)

Juliana Matos Seidel ^[1] ; Sônia Maria Malmonge ^[2]

Afiliação do(s) autor(es)

^[1] Universidade Estadual de Campinas. Centro de Tecnologia. Laboratório de Engenharia Biomecânica - Brasil

^[2] Universidade Estadual de Campinas. Centro de Tecnologia. Laboratório de Engenharia Biomecânica - Brasil

• Tipo de documento: Artigo Científico
• Fonte: MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS; v. 3, n. 3, p. 79-83, 2000-07-00.

Resumo

Dense and porous polyHEMA hydrogels were synthesized by bulk and solution radical-initiated polymerization techniques. The morphologic analysis (SEM) of obtained hydrogels showed an amorphous dense structure for the samples obtained by bulk polymerization and a porous structure with non connected porous as a result of bulk polymerization in the presence of water soluble crystals (sucrose/NaCl). The use of solution polymerization technique using different amounts of water as diluent resulted in the formation of a sponge-like structure with connected microporous in case of using water amount equal or higher than 57.5%. The saline solution uptake and dynamic mechanical behavior of dense hydrogels were influenced by the amount of crosslinking between the polymer chains. (AU)

• Processo FAPESP: 96/10201-6 - Desenvolvimento de polimeros biomimeticos para reparo de defeitos da cartilagem articular.
• Beneficiário: Sônia Maria Malmonge
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado