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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Single nucleotide polymorphisms in genes linked to ion transport and regulation of appetite and their associations with weight gain, feed efficiency and intake of Nellore cattle

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Autor(es):
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Santana, M. H. A. [1] ; Gomes, R. C. [2] ; Ozawa, G. M. [1] ; Fukumasu, H. [1] ; Silva, S. L. [1] ; Leme, P. R. [1] ; Rossi Junior, P. [3] ; Pires, P. R. L. [1] ; Alexandre, P. A. [1] ; Oliveira, P. S. [1] ; Meirelles, F. V. [1] ; Ferraz, J. B. S. [1]
Número total de Autores: 12
Afiliação do(s) autor(es):
[1] Fac Zootecnia & Engn Alimentos USP, BR-13635900 Pirassununga, SP - Brazil
[2] CNPGC EMBRAPA, Empresa Brasileira Pesquisa Agr, BR-79002970 Campo Grande, MS - Brazil
[3] Univ Fed Parana SCA UFPR, BR-80035050 Curitiba, PR - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: LIVESTOCK SCIENCE; v. 165, p. 33-36, JUL 2014.
Citações Web of Science: 0
Resumo

The aim of this study was to evaluate the effects of associations and allele substitution of DNA single nucleotide polymorphism (SNP) on genes linked to appetite control (NPY and PDE3B) and ion transport (ITPR1 and TRPM3) of average daily gain (ADG), feed conversion ratio (FCR), residual feed intake (RFI), residual BW gain (RWG), residual intake and body weight gain (RIG) and dry matter intake (DMI) of Nellore (Bos indicus) cattle. We evaluated the DMI, body weight and ADG of two hundred fifty-one animals kept in feedlots. The data were used to calculate the FCR, RFI, RWG and RIG. The associations of these variables with four SNPs (one in each gene cited above) were analyzes and the effects of allele substitution were estimated using PROC MIXED of SAS 9.3. The SNPs showed no association in genes ITPR1, 7RPM3 and NPY, but we observed a significant association (P <= 0.05) and effect of allele substitution in one SNP in gene PDE3B with DMI. RFI and RIG. The SNPs evaluated are polymorphic in Nellore cattle and the gene PDE3B should be further studied because it seems to have effect on feed intake and efficiency. (C) 2014 Elsevier B.V. All rights reserved. (AU)

Processo FAPESP: 12/03551-5 - Estudo genômico da ingestão e eficiência alimentar em bovinos da raça Nelore
Beneficiário:Miguel Henrique de Almeida Santana
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 12/02039-9 - Estudo genômico da ingestão e eficiência alimentar em bovinos da raça Nelore
Beneficiário:José Bento Sterman Ferraz
Linha de fomento: Auxílio à Pesquisa - Regular