Hormonal Oscillations During the Estrous Cycle Influence the Morphophysiology of the Gerbil (Meriones unguiculatus) Female Prostate (Skene Paraurethral Glands)

Autor(es)

Fochi, Ricardo A. ^[1] ; Perez, Ana P. S. ^[2] ; Bianchi, Carlos V. ^[3] ; Rochel, Sabrina S. ^[4] ; Goes, Rejane M. ^[5] ; Vilamaior, Patricia S. L. ^[6] ; Taboga, Sebastiao R. ^[7] ; Santos, Fernanda C. A. ^[8]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas. UNICAMP

^[2] Univ Estadual Campinas. UNICAMP

^[3] Sao Paulo State Univ. UNESP

^[4] Univ Estadual Campinas. UNICAMP

^[5] Sao Paulo State Univ. UNESP

^[6] UNIRP. Rio Preto Univ Ctr

^[7] Sao Paulo State Univ. UNESP

^[8] Sao Paulo State Univ. UNESP

• Tipo de documento: Artigo Científico
• Fonte: BIOLOGY OF REPRODUCTION; v. 79, n. 6, p. 1084-1091, DEC 2008.
• Citações Web of Science: 17

Resumo

The hormonal oscillations that occur during the female reproductive cycle influence the morphophysiology of several organs of the reproductive system. The female prostate is a functional organ sensitive to the action of steroidal hormones, but it is not known whether the hormonal oscillations that occur during the reproductive cycle can alter the biology of this gland. Thus, the present work aims to evaluate the morphofunctional aspects of the female prostate during the gerbil estrous cycle. For this purpose, morphological, morphometric-stereological, serological, and immunocytochemical analyses were carried out. The results of the present study show that the hormonal oscillations that occurred during the estrous cycle altered both the structure and functionality of the gerbil female prostate. These alterations include increased prostatic growth and augmented secretory activity during the proestrus and estrus phases and a gradual decrease of the secretory activity and glandular development in the diestrus I and II phases. These cyclical oscillations appear to be determined by the hormonal peaks of estrogen in diestrus II and by the high levels of progesterone during estrus, since the androgen levels remained constant throughout the estrous cycle. (AU)

• Processo FAPESP: 06/06924-6 - Aspectos morfofuncionais da prostata feminina do gerbilo durante o ciclo estral: avaliacao das populacoes celulares no epitelio escretor.
• Beneficiário: Ana Paula da Silva Perez
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 07/00711-3 - Aspectos morfofuncionais da prostata feminina do gerbilo durante o ciclo estral: estudos estruturais e caracterizacao do perfil secretor.
• Beneficiário: Ricardo Alexandre Fochi
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 06/06953-6 - Aspectos morfofuncionais da prostata feminina do gerbilo durante o ciclo estral: avaliacao dos compartimentos epitelial e estromal.
• Beneficiário: Carlos Vitor de Bianchi Sobrinho
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 06/06876-1 - Aspectos morfofuncionais da prostata feminina do gerbilo durante o ciclo estral.
• Beneficiário: Sebastião Roberto Taboga
• Modalidade de apoio: Auxílio à Pesquisa - Regular