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KUNITZ-TYPE RECOMBINANT INHIBITOR

Document type:Patente
Inventor(s): Ana Marisa Chudzinski-Tavassi; Durvanei Augusto Maria; Isabel de Fátima Correia Batista; Paulo Lee Ho
Applicant: Ana Marisa Chudzinski-Tavassi ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; União Química Farmacêutica Nacional S/A
Deposit date: March 2008, 14
INPI register:
PCT/BR2008/000078
IPC: C12N 15/12 C07K 14/435 A61K 38/57 C07K 14/745 C12N 15/15 A61P 7/02
Abstract

The present invention presents a Kunitz-type recombinant inhibitor obtained from a gene cloned from a cDNA library of salivary glands of the Amblyomma cajennense, and the inhibitor named Amblyomin-X has molecular mass of 13,500 Da.


Grantee:Isabel de Fátima Correia Batista
Principal Investigator:Ana Marisa Chudzinski-Tavassi
Institution: Secretaria da Saúde (São Paulo - Estado). Instituto Butantan
Support Opportunities: Scholarships in Brazil - Post-Doctoral