Estudo de Monocamadas Auto-organizadas Binárias de um Novo Tiol de Ancoragem (11-mercaptoundecil-N',N'',N'''-trimetilamônio) naTtransferência de Elétrons com Enzima Glicose Oxidase

• Processo: 18/03634-4
• Modalidade de apoio: Auxílio à Pesquisa - Publicações científicas - Artigo
• Data de Início da vigência: 01 de maio de 2018
• Data de Término da vigência: 31 de outubro de 2018
• Área do conhecimento: Ciências Exatas e da Terra - Química - Química Analítica
• Pesquisador responsável: Marcos Fernando de Souza Teixeira
• Beneficiário: Marcos Fernando de Souza Teixeira
• Instituição Sede: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brasil
• Assunto(s): Eletroanalítica
• Palavra(s)-Chave do Pesquisador: Monocamadas auto-organizadas | Plataforma Sensorial | Eletroanalítica

Resumo

In this study, we explore the fabrication and properties of a sensing electrochemical platform that is based on a novel 11-mercaptoundecyl-N',N'',N'''-trimethylammonium hexacyanoferrate (MAH) and 6-(ferrocenyl)hexanethiol (FT) / glucose oxidase (GOx) on gold substrate. The hexacyanoferrate and ferrocene moieties that were immobilized on the gold surface were examined as electron transfer mediators with the oxidase glucose. The sensing platform, based on 11-mercaptoundecyl-N',N'',N'''-trimethylammonium hexacyanoferrate (MAH) and 6-(ferrocenyl)hexanethiol (FT) / GOx modified gold electrode, shows the potential to work with two distinct mechanisms for electrochemical response. The hexacyanoferrate anion that was anchored at positive edge charge of the 11-mercaptoundecyl-N',N'',N'''-trimethylammonium on the gold surface provided an efficient electron transfer. It was demonstrated that in the design of the GOx/MAH, the FT/Au electrode is facilitating the electron transfer from GOx toward the gold substrate. We believe that this study adds a new facet to nanobioelectronics with applications for biofuels and sensorial platforms. (AU)